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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Arch Phys Med Rehabil. 2016 Sep 22;98(2):303–311.e1. doi: 10.1016/j.apmr.2016.08.473

Table 5.

Results of multivariate predictive models

2.5
Coeff.
Covariate Robust Variance Estimates
OIM* p value Boot-strap p value Jack-knife p value
Diameter of largest met 1.66 0.28 0.003 0.26 0.001 0.2807 0.004
WBRT 2.39 0.85 0.014 0.84 0.013 0.9149 0.026
Cerebellar and/or Brainstem met 2.07 0.74 0.042 0.77 0.051 0.6604 0.026
Expanding + New sites 1.76 0.65 0.124 0.66 0.131 0.6394 0.125
Worst Pain 1.12 0.06 0.040 0.07 0.075 0.0671 0.071
C statistic, (bootstrap 95% CI) 0.75 (0.67 – 0.82)
5.0
Diameter of largest met 1.58 0.30 0.016 0.259 0.005 0.3061 0.021
WBRT 2.19 0.89 0.055 1.0799 0.112 1.0972 0.123
Cerebellar and/or Brainstem met 2.38 1.04 0.048 1.2236 0.092 1.3285 0.126
Expanding + New sites 2.45 1.07 0.041 1.6188 0.176 1.4238 0.129
Worst Pain 1.08 0.07 0.221 0.1065 0.444 0.0856 0.345
C statistic, (bootstrap 95% CI) 0.77 (0.67 – 0.84)
7.5
Diameter of largest met 2.23 0.53 0.001 0.7153 0.012 0.613 0.005
WBRT 3.93 1.95 0.006 2.9758 0.07 2.7786 0.057
Cerebellar and/or Brainstem met 1.88 1.06 0.259 1.8293 0.514 1.4871 0.425
Expanding + New sites 3.45 1.85 0.021 2.9356 0.145 2.3222 0.07
Worst Pain 1.15 0.09 0.066 0.1518 0.278 0.1159 0.16
C statistic, (bootstrap 95% CI) 0.83 (0.68 – 0.90)
10
Diameter of largest met 1.96 0.48 0.006 0.6104 0.031 0.508 0.012
WBRT 3.69 2.01 0.017 2.1764 0.027 2.3426 0.044
Cerebellar and/or Brainstem met 2.72 1.79 0.128 3.0791 0.376 1.9453 0.165
Expanding + New sites 1.69 1.04 0.392 1.17 0.447 1.1186 0.429
Worst Pain 1.19 0.10 0.034 0.1725 0.225 0.1442 0.151
C statistic, (bootstrap 95% CI) 0.8 (0.65 – 0.90)
*

Observed Information Matrix