Fig. 1.

The top portion of this figure shows the DNA sequence chromatograms of the four mutations identified in the GRM6 gene in patients with night blindness. For each mutation displayed, the top chromatogram is the mutant sequence, and the bottom is wild-type sequence. The sequence listed above the chromatograms corresponds with the mutant sequence, with the wild-type base listed below. The wild-type codons are shown above the sequence. The sequence and chromatograms for the mutation Gly-150 → Ser are shown in the antisense direction. The bottom portion of the figure shows the analysis of these mutations in the available relatives of the patients. The number to the top left of each pedigree is the family identifier. The genotype of each patient tested is listed below the patient symbol. The probands are marked with arrows.