Figure 4.
Effect of inflammatory cytokines (IL-1β, IFN-γ, and TNF-α) in standard culture (5.5 mM) on human islet metabolism shown using MetaboLync Pathway Classification Network for both media (top) and cell (bottom) samples for the Lipid and Amino Acid super-families. Within each pathway, the size of the circle correlates with the magnitude of change, and the color indicates significant change vs. control (p < 0.05; red increased, blue decreased).