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. Author manuscript; available in PMC: 2018 Jun 2.
Published in final edited form as: J Proteome Res. 2017 May 9;16(6):2294–2306. doi: 10.1021/acs.jproteome.7b00160

Figure 4.

Figure 4

Effect of inflammatory cytokines (IL-1β, IFN-γ, and TNF-α) in standard culture (5.5 mM) on human islet metabolism shown using MetaboLync Pathway Classification Network for both media (top) and cell (bottom) samples for the Lipid and Amino Acid super-families. Within each pathway, the size of the circle correlates with the magnitude of change, and the color indicates significant change vs. control (p < 0.05; red increased, blue decreased).