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Cancer cell growth inhibitory activity of compound 8c and sunitinib toward sensitive (A-549) and resistant NCI-H69AR cancer cell lines
| Compound | IC50 (µM)
|
Fold resistance | |
|---|---|---|---|
| Sensitive A-549 | Resistant NCI-H69AR | ||
| 8c | 1.3±1.5 | 9.5±0.6 | 7.5 |
| Sunitinib | 3.1±0.9 | 5.8±0.4 | 1.9 |
Abbreviation: IC50, inhibitory concentration 50%.
