. Author manuscript; available in PMC: 2017 Dec 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Oct 27;36(12):2452–2459. doi: 10.1161/ATVBAHA.116.307948

Table 3.

Relations of Vascular Measures with Brachial Artery Flow Reversal

	Age-Sex-Cohort			Multivariable^*
	Flow Reversal			Flow Reversal
	Yes N=1994	No N=3714		Yes N=1994	No N=3714
Measurement	LSM (SE)^**	LSM(SE)	P	LSM (SE)	LSM(SE)	P
Baseline brachial diameter, mm	4.11 (0.01)	4.22 (0.01)	<0.0001	4.16 (0.03)	4.20 (0.03)	<0.01
Flow-mediated dilation, %	3.9 (0.08)	4.9 (0.06)	<0.0001	3.9 (0.17)	5.0 (0.16)	<0.0001
Hyperemic Flow velocity, cm/s	53 (0.46)	60 (0.33)	<0.0001	50 (0.99)	57 (0.93)	<0.0001
Carotid-Femoral PWV^***, m/s	8.3 (0.05)	8.1 (0.04)	0.0016	9.3 (0.10)	8.9 (0.09)	<0.0001
Carotid-Radial PWV, m/s	9.5 (0.03)	9.8 (0.02)	<0.0001	9.6 (0.07)	9.8 (0.06)	<0.0001
Baseline FVR (resting), (log dyne · s−1 · cm−5)	5.38 (0.01)	4.64 (0.01)	<0.0001	5.32 (0.03)	4.66 (0.02)	<0.0001

Multivariable model adjusted for age, sex, cohort, mean arterial pressure, heart rate, body-mass index, total/high density lipoprotein cholesterol ratio, triglycerides, glucose, diabetes, current smoking, hypertension treatment, lowering lipid treatment, walk test (before), prevalent CVD.

^**

LSM = least squares mean, SE = standard error.

^***

PWV = pulse wave velocity.