Table 4.
Multivariate model of factors associated with undergoing aggressivea treatment for clinically localized cancer (n = 2796).
| Variable | Received aggressive treatment | Wald F P-value | |
| Adjusted percentages (95% CI) | Odds ratio (95% CI) | ||
| Screening history | 0.05 | ||
| Not-screened | 76 (74, 78) | 1.0 | |
| Screened | 70 (64, 76) | 1.5 (1.1 – 2.3) | |
| SEER registry | < 0.01 | ||
| Los Angeles | 71 (67, 75) | 1.0 | |
| Atlanta | 89 (85, 93) | 4.8 (2.7 – 8.5) | |
| Connecticut | 77 (73, 81) | 1.5 (1.1 – 2.2) | |
| New Mexico | 72 (66, 78) | 1.1 (0.7 – 1.7) | |
| Seattle | 73 (67, 79) | 1.2 (0.8 – 1.8) | |
| Utah | 77 (73, 81) | 1.5 (1.0 – 2.3) | |
| Ethnicity | < 0.01 | ||
| Non-Hispanic white | 76 (74, 78) | 1.0 | |
| Non-Hispanic black | 69 (63, 75) | 0.6 (0.4 – 0.9) | |
| Hispanic | 79 (75, 83) | 1.2 (0.8 – 1.9) | |
| Age | < 0.01 | ||
| < 49 | 95 (92, 100) | 1.0 | |
| 50–64 | 89 (87, 91) | 0.4 (0.2 – 1.2) | |
| 65–74 | 79 (77, 81) | 0.2 (0.1 – 0.5) | |
| 75+ | 41 (35, 47) | 0.03 (0.01 – 0.08) | |
| Current marital status | < 0.01 | ||
| Married | 77 (75, 79) | 1.0 | |
| Unmarried | 71 (67, 75) | 0.6 (0.5 – 0.8) | |
| Education | 0.95 | ||
| < High school degree | 76 (72, 80) | 1.0 | |
| High school/college | 76 (74, 78) | 1.0 (0.7 – 1.3) | |
| College degree | 76 (72, 80) | 0.9 (0.7 – 1.4) | |
| Insurance | 0.25 | ||
| Private | 76 (74, 78) | 1.0 | |
| Medicare/Public | 74 (68, 80) | 0.9 (0.6 – 1.4) | |
| Unknown | 81 (75, 87) | 1.6 (0.9 – 2.8) | |
| Income (annual) | 0.98 | ||
| < $20,000 | 76 (72, 80) | 1.0 | |
| $20 – 40,000 | 76 (72, 80) | 1.0 (0.7 – 1.4) | |
| $40,000 + | 76 (72, 80) | 1.0 (0.7 – 1.5) | |
| Comorbid conditions | 0.01 | ||
| None | 78 (74, 82) | 1.0 | |
| 1 | 77 (73, 81) | 0.9 (0.7 – 1.2) | |
| 2 | 77 (73, 81) | 0.9 (0.6 – 1.3) | |
| 3+ | 68 (62, 74) | 0.5 (0.3 – 0.7) | |
| Health status | < 0.01 | ||
| Excellent | 80 (76, 84) | 1.0 | |
| Good | 77 (75, 79) | 0.8 (0.5 – 1.2) | |
| Fair or poor | 67 (61, 73) | 0.4 (0.3 – 0.7) | |
| PSA (ng/ml) | < 0.01 | ||
| <4 | 69 (63, 75) | 1.0 | |
| ≥ 4 | 77 (75, 79) | 1.7 (1.1 – 2.6) | |
| Unknown | 68 (60, 76) | 0.9 (0.5 – 1.9) | |
| Gleason score | < 0.01 | ||
| 2 – 4 | 68 (62, 74) | 1.0 | |
| 5 – 7 | 78 (76, 80) | 2.0 (1.4 – 2.8) | |
| 8 – 10 | 71 (65, 77) | 1.2 (0.7 – 2.0) | |
| Unknown | 80 (74, 86) | 2.3 (1.3 – 4.2) | |
aAggressive treatment was defined as radical prostatectomy or radiation therapy.
Legend: SEER = Surveillance, Epidemiology, and End Results; PSA = prostate-specific antigen