Table 3.
Patients characteristics depending on their cirrhosis history
| With cirrhosis n = 35 |
Without cirrhosis n = 128 |
P value | ||
|---|---|---|---|---|
| Age (median [Q1–Q3]) | 56 [50–67.5] | 73 [56–83] | 0.0006 | |
| Sex (men; n, %) | 26 (74%) | 69 (54%) | 0.034 | |
| Initial symptoms suggesting UGB, n (%) | Hematemesis | 24 (69) | 60 (47) | 0.005 |
| Melena | 7 (20) | 60 (47) | ||
| Hematochezia | 1 (3) | 6 (5) | ||
| Other | 2 (2) | 3 (9) | ||
| Exteriorized bleeding in the ED, n (%)a | 21 (62) | 69 (54) | 0.56 | |
| Clinical features of severity, n (%)b | n = 32 | n = 127 | ||
| Heart rate > 100 bpm | 17 (53) | 26 (20) | 0.0006 | |
| Systolic arterial pressure < 90 mmHg | 9 (28) | 22 (17) | 0.21 | |
| Marbling | 4 (13) | 3 (2) | 0.031 | |
| Altered mental status | 4 (13) | 2 (2) | 0.015 | |
| Hemoglobin level, n (%)b | < 7 g/dL | 10 (29) | 26 (21) | 0.35 |
| Upper endoscopy in ED, n (%)c | 29 (26) | 9 (29) | 0.82 | |
| Hemostatic procedured | 5 (17) | 5 (5) | 0.036 | |
| Treatments in ED, n (%) | n = 35 | n = 128 | ||
| Nasogastric tube | 5 (14) | 12 (9) | 0.37 | |
| Fluid administration | 20 (57) | 38 (30) | 0.005 | |
| Transfusion | 16 (46) | 50 (39) | 0.56 | |
| Proton pump inhibitors | 28 (80) | 93 (73) | 0.51 | |
| Vasopressors | 23 (66) | 10 (8) | <0.0001 | |
| Catecholamines | 2 (6) | 1 (1) | 0.12 | |
| Antibioticsc (excluding erythromycin) | 4 (13) | 2 (2) | 0.020 | |
| Vitamin K antagonist reversal | 0 | 19 (15) | 0.027 | |
| Erythromycin | 6 (17) | 9 (7) | 0.09 | |
| Final diagnosise (hospitalized patients), n (%) | Ulcer | 2 (6) | 38 (37) | <0.0001 |
| Gastritis | 3 (9) | 12 (12) | ||
| Variceal bleeding | 25 (74) | 1 (1) | ||
| Esophagitis | 2 (6) | 9 (9) | ||
| Mallory-Weiss tear | 0 | 6 (6) | ||
| Cancer | 0 | 12 (12) | ||
| Lower GI bleeding | 0 | 6 (6) | ||
| None | 2 (6) | 19 (18) | ||
afor 161 of 163 patients
bfor 159 of 163 patients
cfor 143 of 163 patients
dfor 141 of 163 patients
efor 137 of 163 patients