Table 4.
Survivors n = 172a | Dead n = 21a | P value | ||
---|---|---|---|---|
Age (median [Q1–Q3])b | 66.5 [49–81] | 66 [57–83] | 0.46 | |
Sex (men; n, %) | 91 (53) | 13 (62) | 0.49 | |
Initial symptoms suggesting UGB, n (%) | Hematemesis | 90 (52) | 13 (62) | 0.87 |
Melena | 67 (39) | 8 (38) | ||
Hematochezia | 8 (5) | 0 (0) | ||
Other | 7 (4) | 0 (0) | ||
Medical history and medication, n (%)c | n = 144 | n = 18 | ||
Known cirrhosis | 28 (19) | 7 (39) | 0.071 | |
Known ulcer | 35 (24) | 3 (17) | 0.57 | |
Non-steroid anti-inflammatory drugs | 54 (38) | 8 (44) | 0.61 | |
Antithrombotic agents | 58 (40) | 4 (22) | 0.20 | |
Comorbidity | 12 (8) | 0 (0) | 0.36 | |
Exteriorized bleeding in the ED, n (%)d | 85 (50) | 16 (76) | 0.035 | |
Clinical features of severity, n (%)e | n = 167 | n = 20 | ||
Heart rate > 100 bpm | 39 (23) | 8 (40) | 0.11 | |
Systolic arterial pressure < 90 mmHg | 26 (16) | 9 (45) | 0.004 | |
Marbling | 5 (3) | 3 (15) | 0.042 | |
Altered mental status | 4 (2) | 5 (25) | 0.0008 | |
Hemoglobin level n (%)f | < 7 g/dL | 34 (20) | 5 (24) | 0.55 |
Upper endoscopy in ED, n (%)g | 39 (25) | 5 (31) | 0.57 | |
Hemostatic procedureh | 11 (7) | 1 (7) | 1.00 | |
Treatments in ED, n (%) | n = 172 | n = 21 | ||
Nasogastric tube | 18 (10) | 1 (5) | 0.70 | |
Fluid administration | 58 (34) | 8 (38) | 0.81 | |
Transfusion | 60 (35) | 12 (57) | 0.057 | |
Proton pump inhibitors | 125 (73) | 14 (67) | 0.61 | |
Vasopressors | 25 (15) | 10 (48) | 0.0009 | |
Catecholamines | 1 (1) | 3 (14) | 0.004 | |
Antibioticsg (excluding erythromycin) | 7 (5) | 1 (6) | 0.56 | |
Vitamin K antagonist reversal | 16 (9) | 3 (14) | 0.44 | |
Erythromycin | 15 (9) | 2 (10) | 1.00 | |
Final diagnosis, n (%)i (hospitalized patients) | Ulcer | 41 (29) | 3 (19) | 0.31 |
Gastritis | 15 (11) | 1 (6) | ||
Variceal bleeding | 23 (17) | 7 (44) | ||
Esophagitis | 12 (9) | 0 (0) | ||
Mallory-Weiss tear | 7 (5) | 0 (0) | ||
Cancer | 10 (7) | 2 (13) | ||
Lower GI bleeding | 8 (6) | 1 (6) | ||
None | 23 (17) | 2 (13) |
a1 missing data
bfor 192 of 193 patients
cfor 162 of 193 patients
d for 191 of 193 patients
efor 187 of 193 patients
ffor 188 of 193 patients
gfor 169 of 193 patients
hfor 167 of 193 patients
ifor 155 of 193 patients