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. 2017 Aug 15;12(8):e0183324. doi: 10.1371/journal.pone.0183324

Fig 5. Activation of NOD1 promotes IL-8 synthesis in both infant and adult airway epithelial cell cultures.

Fig 5

(A) NOD1 real time PCR analysis for both infant (n = 4) and adult (n = 9) primary cultures. *p<0.05 as determined by unpaired t-test. (B) Fold change of IL-8 protein in infant (n = 5) or adult (n = 3) primary cultures following treatment with iE-DAP. *p<0.05 by two-way ANOVA followed by Bonferroni’s multiple comparison test. (C) IL-8 protein synthesis in infant (n = 8) or adult (n = 9) primary cultures following treatment with iE-DAP only or iE-DAP in the presence of ML130. *p<0.05 by two-way ANOVA followed by Bonferroni’s multiple comparison test, infant iE-DAP vs infant ML130, infant iE-DAP vs adult ML130. Error bars represent SEM.