Table 4.

Multivariable Cox proportional hazards model for recurrence free survival

Factor	Comparison	Hazard Ratio	95% LCL	95% UCL	P-value
AZGP1 IHC N=835; E=382	Negative/Weak vs. Moderate/Strong	1.39	1.13	1.71	0.002
Log(PSA)	1 unit increase	1.43	1.21	1.68	<.0001
margin	Pos vs. Neg	1.62	1.31	2.02	<.0001
SVI	Pos vs. Neg	2.20	1.58	3.06	<.0001
ECE	Pos vs. Neg	1.26	1.01	1.58	0.04
Gleason	3+4 vs. ≤6	1.19	0.93	1.52	0.16
	4+3 vs. ≤6	1.99	1.47	2.69	<.0001
	8–10 vs. ≤6	1.43	1.02	1.99	0.04
AZGP1 CISH N=811; E=377	Negative/Weak vs. Moderate/Strong	1.28	1.04	1.58	0.02
Log(PSA)	1 unit increase	1.46	1.24	1.73	<.0001
margin	Pos vs. Neg	1.71	1.39	2.12	<.0001
SVI	Pos vs. Neg	2.26	1.62	3.15	<.0001
Gleason	3+4 vs. <=6	1.22	0.96	1.57	0.11
	4+3 vs. <=6	2.12	1.57	2.86	<.0001
	8–10 vs. <=6	1.60	1.15	2.23	0.006