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. 2017 Aug 15;12(8):e0182784. doi: 10.1371/journal.pone.0182784

Table 5. Summary of previous studies on the accuracy and cutoff values of CAP in discriminating steatosis.

Author, year (Reference) Patients
(n)
Etiology (n) Steatosis definition Cut off of steatosis AUROC Sensitivity Specificity
Sasso et al (2010) [22] 115 - Steatosis ≥ 11% 237.7 dB/m 0.91 91% 81%
Meyers et al (2012) [33] 153 Viral hepatitis (67) Steatosis ≥ 10% 283 dB/m 0.81 76% 79%
NAFLD (72)
Others (9)
Le´dinghen et al (2012) [38] 112 NAFLD (28) Steatosis ≥ 11% 215 dB/m 0.84 ≥ 90% -
HCV (40)
Alcohol (6)
Others (38)
Sasso et al (2012) [31] 615 HCV (615) Steatosis ≥ 11% 222 dB/m 0.80 76% 71%
Chon et al (2014) [30] 135 NAFLD (56) Steatosis ≥ 5% 250 dB/m 0.88 73% 95%
HBV (47)
HCV (12)
Lee et al (2016) [29] 183 NAFLD (94) Steatosis ≥ 5% 247 dB/m 0.85 88% 100%
Non-NAFLD (89)

NAFLD, non alcoholic fatty liver disease; HBV, hepatitis B virus; HCV, hepatitis C virus