Table 5. Summary of previous studies on the accuracy and cutoff values of CAP in discriminating steatosis.
Author, year (Reference) | Patients (n) |
Etiology (n) | Steatosis definition | Cut off of steatosis | AUROC | Sensitivity | Specificity |
---|---|---|---|---|---|---|---|
Sasso et al (2010) [22] | 115 | - | Steatosis ≥ 11% | 237.7 dB/m | 0.91 | 91% | 81% |
Meyers et al (2012) [33] | 153 | Viral hepatitis (67) | Steatosis ≥ 10% | 283 dB/m | 0.81 | 76% | 79% |
NAFLD (72) | |||||||
Others (9) | |||||||
Le´dinghen et al (2012) [38] | 112 | NAFLD (28) | Steatosis ≥ 11% | 215 dB/m | 0.84 | ≥ 90% | - |
HCV (40) | |||||||
Alcohol (6) | |||||||
Others (38) | |||||||
Sasso et al (2012) [31] | 615 | HCV (615) | Steatosis ≥ 11% | 222 dB/m | 0.80 | 76% | 71% |
Chon et al (2014) [30] | 135 | NAFLD (56) | Steatosis ≥ 5% | 250 dB/m | 0.88 | 73% | 95% |
HBV (47) | |||||||
HCV (12) | |||||||
Lee et al (2016) [29] | 183 | NAFLD (94) | Steatosis ≥ 5% | 247 dB/m | 0.85 | 88% | 100% |
Non-NAFLD (89) |
NAFLD, non alcoholic fatty liver disease; HBV, hepatitis B virus; HCV, hepatitis C virus