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Cytotoxicity of curcumin and its NPs on C6 cells (A) and HeLa cells (B).
Notes: The cells were incubated with free curcumin, Cur-NPs, or cHP/Cur-NP for 24, 48, or 72 h at 37°C before the MTT assay.
Abbreviations: cHP, cyclic hexapeptide, c(RGDf(N-me)VK)-C; cHP/Cur-NP, cHP-modified curcumin nanoparticles; Cur, curcumin; Cur-NP, curcumin nanoparticles; MTT, 3-(4,5-dimethylthiazol-2-Yl)-2,5-diphenyltetrazolium bromide; NPs, nanoparticles.
