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GC-skew in up- and downstream regions of the TSS. The up- and downstream regions of the TSS, which were 1.0 and 0.5-kb long, were analyzed using data from four species: 7,708 loci for Arabidopsis, 14,868 loci for rice, 14,053 loci for human and 8,344 loci for Drosophila. The graph shows the mean GC-skew values calculated for sequences of the four species using the sliding-window technique (window size = 100 bp; shift size = 1 bp).
