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. 2017 Aug 15;7:8301. doi: 10.1038/s41598-017-08475-z

Table 2.

Comparison of patient characteristics between the 2 groups.

Characteristic Rapid 131I turnover P
Present (n = 590) Absent (n = 1953)
Gender
 Male 126(21.4%) 667(34.2%) <0.0001*
 Female 464(78.6%) 1286(65.8%)
Age(years) 33.0(11–78) 42.0 (10–80) <0.0001**
FT3(pmol/l) 38.2(11.6–50) 31.3(6.6–50) <0.0001**
FT4(pmol/l) 86.5(32.2–100) 78.9(28.0–100) 0.0010**
Disease duration (mons) 12.5(0.3–264) 12.0(0.2–360) 0.1090
ATD
 With 442(74.9%) 1300(66.6%) <0.0001*
 Without 148(25.1%) 653(33.4%)
Time of ATD 6.0(0–240) 2.0 (0–216) 0.0010**
4 h thyroid 131I uptake(%) 42(7–89) 40(9–92) 0.2060
24 h thyroid 131I uptake(%) 75(35–96) 77(32–95) 0.5340
Thyroid weight(g) 68.0(20–212) 48.5(15–212) <0.0001**
Complications
 With 151(25.60%) 511(26.2%) 0.7820
 Without 439(74.4%) 1442(73.8%)
Thyroid nodules
 With 81(13.7%) 283(14.5%) 0.6434
 Without 509(86.3%) 1670(85.5%)
Thyroid textures
 Soft 266(45.1%) 1009 (51.7%) 0.0040*
 Moderate 236(40.0%) 707(36.2%)
 Stiff 88(14.9%) 237(12.1%)
First-dose 131I failure
 With 71(12.0%) 124(6.3%) <0.0001*
 Without 519(88.0%) 1829(93.7%)

Data are presented as count (percentage) or median (range). *P value < 0.01 using chi square test. **P value < 0.01 using Mann–Whitney U test. FT3 = free triiodothyronine, FT4 = free thyroxine, SD = standard deviation, ATD = antithyroid drugs.