Table 1.

Amino acid sequences and physical characteristics of L-K6 and its analogues.

Peptides	Amino acid sequence	MW	Net charge	Mean hydrophobicitya
L-K6	IKKILSKIKKLLK-NH2	1,552.1	+6	11.6
L-K5 V1	IKKIVSKIKKLL-NH2	1,410.0	+5	11.5
L-K6 V1	IKKIVSKIKKLLK-NH2	1,538.1	+6	10.9

^aThe mean hydrophobicity values of the peptides were calculated using the hydrophobicity scales and were represented as the total hydrophobicity (sum of all residue hydrophobicity indices) divided by the number of residues. All residue hydrophobicity indices were defined as follows: Trp, 32.4; Phe, 29.1; Leu, 23.3; Ile, 21.4; Met, 15.7; Tyr, 14.7; Val, 13.4; Pro, 9.0; Cys, 7.6; Lys, 2.8; Glu, 2.8; Ala, 2.8; Thr, 2.3; Asp, 1.6; Arg, 0.6; Gln, 0.6; His, 0; Ser, 0; Gly, 0; and Asn, −0.6.