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. 2017 Aug 15;7:8147. doi: 10.1038/s41598-017-08396-x

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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MTT cell proliferation assay showing an increase in the cell proliferation in APP_swe/ind-overexpressing SH-SY5Y cells. SH-SY5Y cells transfected with the pCAX APP_swe/ind plasmid were treated with different concentrations of osmotin: 0.5 µM, 1 µM, 1.5 µM, 2.0 µM, and 3.0 µM. Significant at p < 0.05. *Significantly different from control; ^#significantly different from the APP-transfected untreated group.