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. 2017 Aug 15;7:8147. doi: 10.1038/s41598-017-08396-x

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(a) Immunoblots showing the protein expression of major APP processing proteins, ADAM 10, BACE1 and APP. The results show the protein expression in the untreated and pCAX APP_swe/ind plasmid-transfected cells and the pCAX APP_swe/ind plasmid transfected cells treated with osmotin for 24 hours. (b) Histogram showing the protein expression of ADAM 10. (c) Histogram showing the protein expression of BACE1. (d) Histogram showing the protein expression of APP. Full-length blots are included in Supplementary information file. Significant at p < 0.05. *Significantly different from the control group. ^#Significantly different from the APP-transfected group.