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. 2017 Aug 15;7:8290. doi: 10.1038/s41598-017-08197-2

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Gross morphology, weight and tear secretory function after ligation-induced injury. The size and weight of rabbit lacrimal glands decreased after reopening of the lacrimal gland main execretory duct from days 0–7 and then gradually recovered from days 10–30 (A,B). The Schirmer test showed a considerable decrease in tear secretion after ligation; it gradually increased to baseline within 10 days after release of the ligature (C). Con = control, D = day.