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. 2017 Aug 15;7:8296. doi: 10.1038/s41598-017-08373-4

Figure 2.

Figure 2

Loss of KRIT1 blunts TNF-α-induced increased ROS. (A) DHE fluorescence in negative control (NC) siRNA or anti-KRIT1 siRNA transfected HPAEC treated +/− 25 ng/ml TNF-α. Images are representative of n = 4 independent experiments. (B) Average DHE intensity per field of view +/− SEM, normalized to NC siRNA + vehicle, n = 16. p = 0.0137 by ANOVA; *p < 0.05 by Tukey’s post-hoc test, n.s., not significant.