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. 2017 Aug 11;18(Suppl 5):554. doi: 10.1186/s12864-017-3911-3

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Distribution of gene-disease associations. The Y-axis scale is logarithmic. a Number (#) of genes associated with diseases. 2672 diseases are distributed with respect to the number of associated genes. 2051 diseases are monogenic; 621 diseases are associated with multiple genes (from 2 to 69). b Number (#) of diseases associated to genes. 3658 genes are distributed with respect to the number of associated diseases. 2544 genes are associated with a single disease; 1114 genes are associated with multiple diseases (from 2 to 16)