Table 2. Overview of Hemostatic Performance (P1–P7).
| # | polymer | %NHS | functional group contenta (mmol NHS/g polymer) | contact angleb (deg) | gelation timec (min) |
|---|---|---|---|---|---|
| P1 | P(nPropOx-c-NHS) | 10 | 0.76 | 36 | 6 |
| P2 | P(nPropOx-c-NHS) | 29 | 2.19 | 57 | 6 |
| P3 | P(nPropOx-c-EtOx-NHS) | 11 | 0.89 | 26 | 3 |
| P4 | P(nPropOx-c-EtOx-NHS) | 24 | 1.59 | 24 | 3 |
| P5 | P(nPropOx-c-EtOx-NHS) | 11 | 0.88 | 23 | 3 |
| P6 | P(nPropOx-c-EtOx-NHS) | 24 | 1.57 | 21 | 3 |
| P7 | P(nPropOx-c-OH-NHS) | 15 | 0.91 | 23 | 1 |
| Controls | |||||
| P8 | P(EtOx) | 26 | no gel | ||
| P9 | P(nPropOx) | 57 | no gel | ||
| P10 | mPEG-OH | 24 | no gel | ||
| P11 | PEG-4-arm-NHSd | 0.36 | 21 | instantaneous | |
a
Calculated using NHS-content, which was determined by 1H NMR spectroscopy.
b
The measurements were conducted in triplo, blank measurement glass slide (66°).
c
The gelation was determined by the inverted vial method.
d
Obtained from commercial source.