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. Author manuscript; available in PMC: 2017 Aug 16.
Published in final edited form as: Curr Biol. 2014 Dec 4;25(1):124–130. doi: 10.1016/j.cub.2014.11.041

Figure 3. Pix and Git control cell number and organ size through Hippo.

Figure 3

(A–G) D. melanogaster eyes (either wildtype or harboring the indicated mutations) 44 hours after puparium formation, stained with anti-Discs-large. (H) Quantification of interommatidial cell numbers of the genotypes displayed in (A–G). n=5 in (A), n=8 in (B), n=10 in (C), n=12 in (D), n=9 in (E), n=3 in (F), n=3 in (G). Data represents mean +/− SEM. * indicates a p-value <0.05, **** indicates a p-value <0.0001. Adult female D. melanogaster wings (H–L) and eyes (N–R) expressing the following transgenes under the control of nub-Gal4 or GMR-Gal4; (H) and (N) UAS-lacZ; (I) and (O) UAS-pix, UAS-git; (J) and (K) and (Q) UAS-hpo, UAS-pix, UAS-git;(L) and (R) UAS-hpo/UAS-hpo. (M) Quantification of wing area of the indicated genotypes. n=19 in (H), n=22 in (I), n=21 in (J), n=16 in (K), n=17 in (L). In (F), data represents mean +/− SEM. *** indicates a p-value <0.001. See also Figure S3.