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. 2016 May 4;17(7):743–753. doi: 10.2217/pgs-2015-0012

Table 4. . Influence of haplotype on the effect of chloride in protecting GSTZ1-1 from inactivation by dichloroacetate.

Haplotype EC50 mM Inactivation half-life, h without Cl- Inactivation half-life, h with 38 mM Cl-
EGT/EGT
15 ± 3.1 (3)
0.53, 0.49
5.73, 5.02
KRT/EGT
36 ± 2.2 (3)
0.38, 0.38
2.66, 2.37
EGM/EGM 16.9 5.55

EC50 is the concentration of chloride that protected half the cytosolic GSTZ1 from inactivation following incubation for 2 h with Na DCA, 0.5 mM.