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. 2017 Jun 25;7(10):2620–2633. doi: 10.7150/thno.18096

Figure 6.

Figure 6

Relative efficacy of in vivo MicroPET imaging of 64Cu-NOTA-rEgA. (A) MicroPET imaging of HT29, H1650, A549, SW620 and MDA-MB-435 tumor-bearing mice (n = 6 per condition) using intravenously injected 64Cu-NOTA-rEgA. For blocking HT-29 and H1650 tumor-bearing mice (n = 6 per condition) were injected with 100 μL of 50 µmol naive rEgA 24 h before injection of 64Cu-NOTA-rEgA. (B) On the subsequent day, the 64Cu-NOTA-rEgA was monitored using microPET at the indicated times post-injection (* P < 0.05). (C) Correlation of EGFR expression level (%) and 6 h PET uptake (%ID/g) by Pearson correlation method (R 2= 0.9154, P = 0.011).