Table 4.
Correlation of HJHS domains with EQ-5D-5L, BPI, SF-36v2, and HAL scores
| Construct | Elbow
|
Ankle
|
Knee
|
Global Gait
|
Total Score
|
|||||
|---|---|---|---|---|---|---|---|---|---|---|
| Pearson’s r | P-value | Pearson’s r | P-value | Pearson’s r | P-value | Pearson’s r | P-value | Pearson’s r | P-value | |
| EQ-5D-5L | ||||||||||
| Domain scores | ||||||||||
| Mobility | 0.39 | <0.01 | 0.50 | <0.01 | 0.40 | <0.01 | 0.22 | <0.01 | 0.50 | <0.01 |
| Self-care | 0.36 | <0.01 | 0.33 | <0.01 | 0.19 | <0.01 | 0.12 | <0.01 | 0.34 | <0.01 |
| Usual activities | 0.33 | <0.01 | 0.39 | <0.01 | 0.30 | <0.01 | 0.06 | <0.01 | 0.40 | <0.01 |
| Pain/discomfort | 0.37 | <0.01 | 0.39 | <0.01 | 0.29 | <0.01 | 0.03 | <0.01 | 0.41 | <0.01 |
| Anxiety/depression | 0.16 | 0.01 | 0.13 | 0.04 | 0.08 | 0.24 | 0.11 | 0.24 | 0.14 | 0.03 |
| Summary scores | ||||||||||
| Index | −0.40 | <0.01 | −0.45 | <0.01 | −0.30 | <0.01 | −0.17 | <0.01 | −0.45 | <0.01 |
| Visual analog scale | −0.35 | <0.01 | −0.28 | <0.01 | −0.24 | <0.01 | −0.13 | <0.01 | −0.33 | <0.001 |
| BPI | ||||||||||
| Domain scores | ||||||||||
| Worst pain | 0.37 | <0.01 | 0.37 | <0.01 | 0.40 | <0.01 | 0.20 | <0.01 | 0.44 | <0.01 |
| Least pain | 0.25 | <0.01 | 0.37 | <0.01 | 0.29 | <0.01 | −0.02 | <0.01 | 0.35 | <0.01 |
| Average pain | 0.35 | <0.01 | 0.39 | <0.01 | 0.38 | <0.01 | 0.10 | <0.01 | 0.44 | <0.01 |
| Current pain | 0.35 | <0.01 | 0.42 | <0.01 | 0.28 | <0.01 | 0.14 | <0.01 | 0.40 | <0.01 |
| Summary scores | ||||||||||
| Pain severity | 0.37 | <0.01 | 0.43 | <0.01 | 0.38 | <0.01 | 0.13 | <0.01 | 0.45 | <0.01 |
| Pain interference | 0.35 | <0.01 | 0.33 | <0.01 | 0.30 | <0.01 | 0.17 | <0.01 | 0.38 | <0.01 |
| SF-36v2 | ||||||||||
| Domain scores | ||||||||||
| Physical functioning | −0.41 | <0.01 | −0.53 | <0.01 | −0.38 | <0.01 | −0.18 | <0.01 | −0.51 | <0.01 |
| Role physical | −0.37 | <0.01 | −0.36 | <0.01 | −0.28 | <0.01 | −0.11 | <0.01 | −0.39 | <0.01 |
| Bodily pain | −0.39 | <0.01 | −0.37 | <0.01 | −0.38 | <0.01 | −0.15 | <0.01 | −0.44 | <0.01 |
| Summary scores | ||||||||||
| Physical health summary | −0.42 | <0.01 | −0.47 | <0.01 | −0.34 | <0.01 | −0.18 | <0.01 | −0.47 | <0.01 |
| Overall health | 0.16 | 0.02 | 0.06 | 0.27 | 0.13 | 0.26 | 0.10 | 0.26 | 0.15 | 0.23 |
| HAL | ||||||||||
| Domain scores | ||||||||||
| Lying/sitting/kneeling/standing | −0.44 | <0.01 | −0.56 | <0.01 | −0.40 | <0.01 | −0.05 | <0.01 | −0.53 | <0.01 |
| Functions of the legs | −0.42 | <0.01 | −0.51 | <0.01 | −0.45 | <0.01 | −0.13 | <0.01 | −0.53 | <0.01 |
| Functions of the arms | −0.44 | <0.01 | −0.41 | <0.01 | −0.27 | <0.01 | −0.15 | <0.01 | −0.42 | <0.01 |
| Use of transportation | −0.44 | <0.01 | −0.53 | <0.01 | −0.30 | <0.01 | −0.09 | <0.01 | −0.48 | <0.01 |
| Self-care | −0.37 | <0.01 | −0.30 | <0.01 | −0.19 | <0.01 | −0.12 | <0.01 | −0.32 | <0.01 |
| Household tasks | −0.43 | <0.01 | −0.42 | <0.01 | −0.28 | <0.01 | −0.12 | <0.01 | −0.42 | <0.01 |
| Leisure activities and sports | −0.36 | <0.01 | −0.41 | <0.01 | −0.32 | <0.01 | −0.13 | <0.01 | −0.41 | <0.01 |
| Summary scores | ||||||||||
| Upper extremity activities | −0.45 | <0.01 | −0.39 | <0.01 | −0.26 | <0.01 | −0.15 | <0.01 | −0.41 | <0.01 |
| Basic lower extremity activities | −0.42 | <0.01 | −0.47 | <0.01 | −0.40 | <0.01 | −0.14 | <0.01 | −0.49 | <0.01 |
| Complex lower extremity activities | −0.46 | <0.01 | −0.59 | <0.01 | −0.45 | <0.01 | −0.07 | <0.01 | −0.58 | <0.01 |
| Overall activity | −0.47 | <0.01 | −0.53 | <0.01 | −0.39 | <0.01 | −0.12 | <0.01 | −0.53 | <0.01 |
Notes: High correlations are defined as r≥0.37. Bold values indicate the strongest correlations with r>0.5.
Abbreviations: BPI, Brief Pain Inventory v2 Short Form; HAL, Hemophilia Activities List; HJHS, Hemophilia Joint Health Score v2.1.