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. Author manuscript; available in PMC: 2017 Aug 16.
Published in final edited form as: J Autoimmun. 2017 Mar 18;81:13–23. doi: 10.1016/j.jaut.2017.03.001

Fig. 5.

Fig. 5

V235fs and D272fs mice produce increased levels of broad range of autoantibodies. (A, B) Mouse serum autoantibody analysis. Representative autoantibodies from autoantibody array analysis are shown. IgG in A and IgM in B. n = 5. Statistical analysis was performed using multiple t-test comparing WT vs V235fs or WT vs D272 fs at each time point. (C, D) Mouse serum antinuclear antibody (ANA) titer before (C) and after (D) injection of apoptotic thymocytes (AT). n = 5. Statistical analysis was performed using t-test comparing WT vs V235fs or WT vs D272fs before treatment (C) and only AT-treated samples in D. *, p < 0.05. **, p < 0.01. ***, p < 0.001. ns, not significant. Error bar, SEM. Data are representative of at least two independent experiments.