Figure 2.

Pathway representation of interconnected proteins that were statistically different between early- and advanced-stage tumours. Members of the LKB1–AMPK and the AKT–mTOR signalling pathways that were highly activated in the early-stage ovarian cancers compared to the advanced stages are represented along with their metabolic functions (A). Box-plots of selected key proteins that reached statistical significance with non-parametric mean comparison illustrate the median and the minimum and maximum values for each group (B).