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. 2017 Jun 29;117(4):470–477. doi: 10.1038/bjc.2017.202

Table 1. The modified geriatric assessmenta.

Domain Scale Range Rated by Cutoff value for frailty Rationale for cutoff values
Activities of daily living EORTC QLQ-C30 Q5b   Patient If reported yes a little/quite a bit/very much on the question ‘Do you need help with eating, dressing, washing yourself or using the toilet’ ADL-deficiencies previously used in frailty classifications of cancer patients (Balducci and Extermann, 2000)
Comorbidity OARSc 0–15 (Higher score indicates more comorbidities) Patient >3 points Threshold for shorter survival in previous study of cancer patients (Klepin et al, 2014)
Medications, polypharmacy ATCd 0–13 Nurse/ MD >7 regular medications (ointments & common vitamins excluded) Previously used in frailty classifications of cancer patients (Ommundsen et al, 2014)
Physical function TUGe   Nurse >14 seconds Similar cut-offs (⩾14/>14.5) used to identify GA deficits in cancer trials (Owusu et al, 2011; Jolly et al, 2015; Williams et al, 2015)
Cognitive function MMSEf 0–30 (Higher score indicates better function) Nurse <24 points Previously used in frailty classifications of cancer patients (Ommundsen et al, 2014)
Depressive symptoms GDS-15g 0–15 (Higher score indicates more symptoms) Patient ⩾7 points Chosen to ensure high specificity (Friedman et al, 2005; Cullum et al; 2006)
Nutritional status PG-SGAh   Nurse/Patient Considered severely malnourished by nurse or self-reported weight loss ⩾10% the last 6 months. Weight loss ⩾ 10% the last six months is generally considered as an indicator of severe malnutrition (Nitenberg and Raynard, 2000)
Falls     Nurse Patient reports ⩾2 falls the last 6 months Previously used to identify GA deficits in cancer trials (Owusu et al, 2011; Jolly et al, 2015)
a

Patients were classified as mGA-frail if having ⩾ 1 of the criteria listed in the table.

b

The European Organisation for Research and Treatment of Cancer Quality of Life Core Questionnaire.

c

The Physical Health Section of the Older Americans’ Resources and Services Questionnaire.

d

Anatomical Therapeutic Chemical Classification System.

e

Timed up and Go test.

f

Norwegian Revised Mini Mental State Examination.

g

Geriatric depression scale.

h

Patient-generated Subjective Global Assessment.