Table 1. The modified geriatric assessmenta.
Domain | Scale | Range | Rated by | Cutoff value for frailty | Rationale for cutoff values |
---|---|---|---|---|---|
Activities of daily living | EORTC QLQ-C30 Q5b | Patient | If reported yes a little/quite a bit/very much on the question ‘Do you need help with eating, dressing, washing yourself or using the toilet’ | ADL-deficiencies previously used in frailty classifications of cancer patients (Balducci and Extermann, 2000) | |
Comorbidity | OARSc | 0–15 (Higher score indicates more comorbidities) | Patient | >3 points | Threshold for shorter survival in previous study of cancer patients (Klepin et al, 2014) |
Medications, polypharmacy | ATCd | 0–13 | Nurse/ MD | >7 regular medications (ointments & common vitamins excluded) | Previously used in frailty classifications of cancer patients (Ommundsen et al, 2014) |
Physical function | TUGe | Nurse | >14 seconds | Similar cut-offs (⩾14/>14.5) used to identify GA deficits in cancer trials (Owusu et al, 2011; Jolly et al, 2015; Williams et al, 2015) | |
Cognitive function | MMSEf | 0–30 (Higher score indicates better function) | Nurse | <24 points | Previously used in frailty classifications of cancer patients (Ommundsen et al, 2014) |
Depressive symptoms | GDS-15g | 0–15 (Higher score indicates more symptoms) | Patient | ⩾7 points | Chosen to ensure high specificity (Friedman et al, 2005; Cullum et al; 2006) |
Nutritional status | PG-SGAh | Nurse/Patient | Considered severely malnourished by nurse or self-reported weight loss ⩾10% the last 6 months. | Weight loss ⩾ 10% the last six months is generally considered as an indicator of severe malnutrition (Nitenberg and Raynard, 2000) | |
Falls | Nurse | Patient reports ⩾2 falls the last 6 months | Previously used to identify GA deficits in cancer trials (Owusu et al, 2011; Jolly et al, 2015) |
Patients were classified as mGA-frail if having ⩾ 1 of the criteria listed in the table.
The European Organisation for Research and Treatment of Cancer Quality of Life Core Questionnaire.
The Physical Health Section of the Older Americans’ Resources and Services Questionnaire.
Anatomical Therapeutic Chemical Classification System.
Timed up and Go test.
Norwegian Revised Mini Mental State Examination.
Geriatric depression scale.
Patient-generated Subjective Global Assessment.