Table 2. Baseline patient characteristics according to the mGA and the oncologists’ classification.
Modified geriatric assessment |
The oncologists classification |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
mGA-frail |
mGA-non-frail |
Onc-frail |
Onc-non-frail |
|||||||||
N (288) | % | N (140) | % | N (148) | % | P-value | N (104) | % | N (182) | % | P-value | |
Age, mean (s.d.) | 76.9 (5.1) | 77.5 (5.2) | 76.2 (5.0) | 0.032a | 77.2 (5.4) | 76.6 (5.0) | 0.346a | |||||
Gender | ||||||||||||
Female | 126 | 44 | 64 | 46 | 62 | 42 | 0.513b | 43 | 41 | 81 | 45 | 0.604b |
Cancer type | ||||||||||||
Colorectal | 83 | 29 | 39 | 28 | 44 | 30 | 18 | 17 | 64 | 35 | ||
Lung | 59 | 21 | 35 | 25 | 24 | 16 | 34 | 33 | 25 | 14 | ||
Prostate | 56 | 19 | 22 | 16 | 34 | 23 | 0.045b | 25 | 24 | 31 | 17 | <0.001b |
Other gastrointestinal | 34 | 12 | 19 | 14 | 15 | 10 | 8 | 8 | 25 | 14 | ||
Breast | 30 | 10 | 9 | 6 | 21 | 14 | 6 | 6 | 24 | 13 | ||
Other | 26 | 9 | 16 | 11 | 10 | 7 | 13 | 13 | 13 | 7 | ||
Stage | ||||||||||||
Localised | 73 | 25 | 30 | 21 | 43 | 29 | 12 | 12 | 61 | 34 | ||
Locally advanced | 55 | 19 | 23 | 16 | 32 | 22 | 0.091b | 22 | 21 | 32 | 18 | <0.001b |
Distant metastasis | 160 | 56 | 87 | 62 | 73 | 49 | 70 | 67 | 89 | 49 | ||
ECOG PS | ||||||||||||
0–1 | 244 | 85 | 106 | 76 | 138 | 93 | 62 | 60 | 181 | 100 | ||
2–4 | 43 | 15 | 33 | 24 | 10 | 7 | <0.001b | 42 | 40 | 0 | <0.001b | |
Missing | 1 | 1 | 0 | 1 | ||||||||
Treatment | ||||||||||||
Curativec | 91 | 32 | 31 | 22 | 60 | 41 | 14 | 14 | 77 | 42 | ||
Palliative chemotherapy | 126 | 44 | 75 | 54 | 51 | 35 | 60 | 58 | 66 | 36 | ||
Other palliative systemic cancer treatment | 51 | 18 | 22 | 16 | 29 | 20 | 0.002b | 21 | 20 | 30 | 17 | <0.001b |
Non-systemic palliative treatmentd | 20 | 7 | 12 | 9 | 8 | 5 | 9 | 9 | 9 | 5 |
Independent samples t-test.
Pearson χ2-test.
Referred for neoadjuvant treatment, adjuvant treatment after curative surgery or curative radiotherapy.
Radiotherapy, palliative surgery or palliative care.
Bold numbers are statistically significant.