Fig. 3.

Tissue specificity of lincRNAs. a: TSI of lincRNAs and protein-coding genes. b: Number of tissue-specific lincRNAs identified from the TSI method (blue) and ‘rsgcc’ package (orange), respectively. c: Expression heatmap of tissue-specific lincRNAs identified using ‘rsgcc’. Columns represent samples while rows represent lincRNAs. d: Expression-based correlation matrix of 534 tissue-specific lincRNAs from ‘rsgcc’ (column) and 340 GSEA GO gene sets (row). Blue denotes a negative correlation, red a positive association, and white shows no significant relationship. These GO sets were divided into 11 clusters (right) based on their functional similarity and correlation