Table 1.

Expression of neonatal (PN2) hypothalamic miRNAs with statistically significant sex differences

miRNA annotations (mirbase)				Log2 fold change (relative to F/Veh)
miRNA	Accession	Family	Alignment (mm9)	F/Veh	M/Form	M/Veh	Effect
mmu-let-7a-2	MI0000557	let-7	9:41344799–41344894 (+)	0.0 ± 0.09A	−0.103 ± 0.08AB	−0.360 ± 0.11B	Estrogen (down)
mmu-let-7c-2-3p	MIMAT0005439	let-7	15:85537033–85537127 (+)	0.0 ± 0.06A	0.021 ± 0.03A	−0.276 ± 0.11B	Estrogen (down)
mmu-mir-101a	MI0000148	mir-101	4:101019550–101019632 (−)	0.0 ± 0.07A	−0.012 ± 0.11A	0.302 ± 0.07B	Estrogen (up)
mmu-miR-10b-3p	MIMAT0004538	mir-10	2:74564127–74564194 (+)	0.0 ± 0.07A	−0.058 ± 0.09AB	−0.303 ± 0.07B	Estrogen (down)
mmu-miR-1186	MIMAT0005836		8:32213393–32213514 (−)	0.0 ± 0.14A	0.467 ± 0.16B	0.866 ± 0.19B	Estrogen (up)
mmu-miR-1186b	MIMAT0015644		8:98487444–98487507 (+)	0.0 ± 0.15A	0.444 ± 0.14AB	0.742 ± 0.21B	Other (up)
mmu-miR-1188-3p	MIMAT0017328	mir-1188	12:110850032–110850151 (+)	0.0 ± 0.04A	−0.121 ± 0.13AB	−0.410 ± 0.13B	Estrogen (down)
mmu-miR-1188-5p	MIMAT0005843	mir-1188	12:110850032–110850151 (+)	0.0 ± 0.04A	−0.344 ± 0.19AB	−0.509 ± 0.11B	Estrogen (down)
mmu-miR-1192	MIMAT0005850		19:23223921–23224041 (+)	0.0 ± 0.15A	−0.192 ± 0.13A	1.134 ± 0.64B	Estrogen (up)
mmu-mir-1196	MI0006304		14:62371057–62371175 (−)	0.0 ± 0.06A	−0.066 ± 0.11AB	−0.359 ± 0.1B	Estrogen (down)
mmu-mir-1199	MI0006307		8:86535414–86535532 (−)	0.0 ± 0.21A	−0.196 ± 0.1AB	−0.551 ± 0.15B	Estrogen (down)
mmu-miR-1247-5p	MIMAT0014800	mir-1247	12:111516258–111516339 (−)	0.0 ± 0.18A	0.195 ± 0.12A	0.618 ± 0.18B	Estrogen (up)
mmu-miR-1249-3p	MIMAT0010560	mir-1249	15:84781956–84782053 (−)	0.0 ± 0.14A	1.315 ± 0.47B	1.405 ± 0.39B	Other (up)
mmu-miR-1251-3p	MIMAT0014825	mir-1251	10:91599885–91599968 (−)	0.0 ± 0.1A	−0.213 ± 0.13AB	−0.447 ± 0.15B	Estrogen (down)
mmu-miR-1251-5p	MIMAT0014824	mir-1251	10:91599885–91599968 (−)	0.0 ± 0.18A	−0.412 ± 0.16AB	−0.486 ± 0.14B	Other (down)
mmu-miR-127-3p	MIMAT0000139	mir-127	12:110831056–110831125 (+)	0.0 ± 0.07A	−0.116 ± 0.14AB	−0.391 ± 0.1B	Estrogen (down)
mmu-miR-127-5p	MIMAT0004530	mir-127	12:110831056–110831125 (+)	0.0 ± 0.08A	−0.122 ± 0.08AB	−0.290 ± 0.03B	Estrogen (down)
mmu-mir-134	MI0000160	mir-134	12:110972349–110972419 (+)	0.0 ± 0.06A	−0.055 ± 0.07AB	−0.290 ± 0.11B	Estrogen (down)
mmu-miR-134-5p	MIMAT0000146	mir-134	12:110972349–110972419 (+)	0.0 ± 0.07A	−0.207 ± 0.11AB	−0.429 ± 0.09B	Estrogen (down)
mmu-miR-135a-1-3p	MIMAT0004531	mir-135	9:106056455–106056544 (+)	0.0 ± 0.09A	−0.267 ± 0.16AB	−0.451 ± 0.13B	Other (down)
mmu-miR-135b-5p	MIMAT0000612	mir-135	1:134094665–134094761 (+)	0.0 ± 0.14A	−0.340 ± 0.09A	−0.809 ± 0.2B	Other (down)
mmu-miR-138-1-3p	MIMAT0004668	mir-138	9:122591994–122592092 (+)	0.0 ± 0.04A	−0.109 ± 0.14AB	−0.217 ± 0.05B	Estrogen (down)
mmu-miR-149-5p	MIMAT0000159	mir-149	1:94746955–94747020 (+)	0.0 ± 0.11A	0.648 ± 0.24B	0.619 ± 0.23B	Other (up)
mmu-miR-150-5p	MIMAT0000160	mir-150	7:52377127–52377191 (+)	0.0 ± 0.04A	−0.070 ± 0.1AB	−0.323 ± 0.11B	Estrogen (down)
mmu-miR-15a-5p	MIMAT0000526	mir-15	14:62250864–62250947 (−)	0.0 ± 0.14A	−0.154 ± 0.14AB	−0.581 ± 0.29B	Estrogen (down)
mmu-miR-181b-2-3p	MIMAT0017084	mir-181	2:38709350–38709438 (+)	0.0 ± 0.04A	0.240 ± 0.08AB	0.320 ± 0.08B	Other (up)
mmu-miR-184-3p	MIMAT0000213	mir-184	9:89697098–89697166 (−)	0.0 ± 0.1A	−0.613 ± 0.2B	−0.759 ± 0.26B	Other (down)
mmu-miR-1843b-3p	MIMAT0019346	mir-1843	1:161270489–161270554 (+)	0.0 ± 0.12A	0.286 ± 0.08B	0.345 ± 0.08B	Other (up)
mmu-miR-185-5p	MIMAT0000214	mir-185	16:18327494–18327558 (−)	0.0 ± 0.18A	−0.265 ± 0.26AB	−0.738 ± 0.12B	Estrogen (down)
mmu-mir-188	MI0000230	mir-188	X:6825115–6825182 (−)	0.0 ± 0.07A	−0.094 ± 0.09AB	−0.349 ± 0.13B	Estrogen (down)
mmu-mir-1904	MI0008323		13:110694017–110694096 (+)	0.0 ± 0.07A	−0.212 ± 0.09AB	−0.268 ± 0.06B	Other (down)
mmu-miR-1930-3p	MIMAT0017340		10:77103969–77104052 (+)	0.0 ± 0.1A	−0.267 ± 0.11AB	−0.384 ± 0.16B	Estrogen (down)
mmu-mir-1936	MI0009925		12:103923138–103923230 (−)	0.0 ± 0.05A	0.076 ± 0.04AB	0.288 ± 0.12B	Estrogen (up)
mmu-mir-1938	MI0009927		12:40949299–40949398 (−)	0.0 ± 0.07A	−0.174 ± 0.06AB	−0.344 ± 0.09B	Other (down)
mmu-miR-194-1-3p	MIMAT0016999	mir-194	1:187137198–187137264 (+)	0.0 ± 0.26A	−0.073 ± 0.13A	−0.517 ± 0.11B	Estrogen (down)
mmu-miR-1955-5p	MIMAT0009426		2:92032134–92032231 (+)	0.0 ± 0.08A	−0.162 ± 0.08AB	−0.413 ± 0.2B	Estrogen (down)
mmu-mir-202	MI0000245	mir-202	7:147143588–147143659 (−)	0.0 ± 0.11A	−0.391 ± 0.06B	−0.456 ± 0.04B	Other (down)
mmu-mir-206	MI0000249	mir-1	1:20669091–20669163 (+)	0.0 ± 0.26A	−0.331 ± 0.06AB	−0.495 ± 0.12B	Other (down)
mmu-miR-210-5p	MIMAT0017052	mir-210	7:148407283–148407392 (−)	0.0 ± 0.07A	−0.083 ± 0.08AB	−0.332 ± 0.12B	Estrogen (down)
mmu-mir-214	MI0000698	mir-214	1:164153499–164153608 (+)	0.0 ± 0.16A	−0.069 ± 0.1A	−0.454 ± 0.15B	Estrogen (down)
mmu-miR-216a-5p	MIMAT0000662	mir-216	11:28657012–28657083 (+)	0.0 ± 0.17A	−0.189 ± 0.17AB	−0.473 ± 0.11B	Estrogen (down)
mmu-miR-217-3p	MIMAT0017072	mir-217	11:28663728–28663835 (+)	0.0 ± 0.1A	−0.139 ± 0.09AB	−0.382 ± 0.1B	Estrogen (down)
mmu-mir-218-1	MI0000700	mir-218	5:48615181–48615290 (+)	0.0 ± 0.1A	−0.058 ± 0.12AB	−0.384 ± 0.1B	Other (down)
mmu-miR-218-1-3p	MIMAT0004665	mir-218	5:48615181–48615290 (+)	0.0 ± 0.08A	−0.307 ± 0.1AB	−0.474 ± 0.16B	Other (down)
mmu-miR-219-1-3p	MIMAT0017055	mir-219	17:34161928–34162037 (−)	0.0 ± 0.12A	−0.633 ± 0.14B	−0.651 ± 0.16B	Other (down)
mmu-miR-219-2-3p	MIMAT0017074	mir-219	2:29701151–29701247 (−)	0.0 ± 0.1A	−0.063 ± 0.08A	−0.394 ± 0.12B	Other (down)
mmu-miR-222-5p	MIMAT0017061	mir-221	X:18724019–18724097 (−)	0.0 ± 0.1A	−0.293 ± 0.09B	−0.393 ± 0.09B	Other (down)
mmu-miR-27b-3p	MIMAT0000126	mir-27	13:63402020–63402092 (+)	0.0 ± 0.05A	−0.155 ± 0.1AB	−0.509 ± 0.17B	Other (down)
mmu-miR-28-3p	MIMAT0004661	mir-28	16:24827941–24828026 (+)	0.0 ± 0.04A	−0.194 ± 0.05AB	−0.298 ± 0.06B	Other (down)
mmu-miR-292-3p	MIMAT0000370	mir-290	7:3219190–3219271 (+)	0.0 ± 0.03A	−0.217 ± 0.1AB	−0.336 ± 0.09B	Other (down)
mmu-mir-299	MI0000399	mir-299	12:110948848–110948910 (+)	0.0 ± 0.03A	−0.133 ± 0.07AB	−0.359 ± 0.06B	Other (down)
mmu-miR-299-5p	MIMAT0000377	mir-299	12:110948848–110948910 (+)	0.0 ± 0.12A	−0.624 ± 0.21B	−0.615 ± 0.22B	Other (down)
mmu-miR-3057-3p	MIMAT0014823		10:80734342–80734432 (+)	0.0 ± 0.16A	−0.496 ± 0.22B	−0.744 ± 0.05B	Other (down)
mmu-miR-3059-5p	MIMAT0014811		10:101235326–101235406 (+)	0.0 ± 0.23A	−0.340 ± 0.17AB	−0.533 ± 0.1B	Other (down)
mmu-miR-3060-5p	MIMAT0014826		11:4039367–4039449 (+)	0.0 ± 0.05A	−0.159 ± 0.1AB	−0.339 ± 0.12B	Estrogen (down)
mmu-miR-3061-5p	MIMAT0014828		11:51940248–51940338 (+)	0.0 ± 0.07A	−0.456 ± 0.08B	−0.705 ± 0.2B	Other (down)
mmu-miR-3065-3p	MIMAT0014837	mir-3065	11:119876081–119876167 (+)	0.0 ± 0.09A	0.427 ± 0.11B	0.602 ± 0.18B	Other (up)
mmu-mir-3070a	MI0014032	mir-3070	12:110826153–110826241 (+)	0.0 ± 0.1A	−0.270 ± 0.09AB	−0.331 ± 0.11B	Other (down)
mmu-mir-3070b	MI0014033	mir-3070	12:110826802–110826890 (+)	0.0 ± 0.06A	0.075 ± 0.04A	−0.290 ± 0.13B	Estrogen (down)
mmu-miR-3071-3p	MIMAT0014851		12:110833528–110833607 (−)	0.0 ± 0.07A	−0.156 ± 0.06AB	−0.350 ± 0.05B	Estrogen (down)
mmu-miR-3072-5p	MIMAT0014852		12:110986088–110986170 (+)	0.0 ± 0.18A	−0.124 ± 0.13AB	−0.489 ± 0.18B	Estrogen (down)
mmu-miR-3074-1-3p	MIMAT0014857	mir-3074	13:63402507–63402591 (−)	0.0 ± 0.07A	−0.218 ± 0.18AB	−0.634 ± 0.29B	Estrogen (down)
mmu-miR-3078-3p	MIMAT0014865		14:65210022–65210108 (+)	0.0 ± 0.12A	−0.248 ± 0.1AB	−0.547 ± 0.26B	Other (down)
mmu-miR-3082-3p	MIMAT0014873		17:25968310–25968373 (−)	0.0 ± 0.14A	−0.386 ± 0.16AB	−0.489 ± 0.12B	Other (down)
mmu-miR-3093-3p	MIMAT0014908		3:88019093–88019179 (+)	0.0 ± 0.05A	−0.063 ± 0.06AB	−0.322 ± 0.15B	Estrogen (down)
mmu-miR-3097-5p	MIMAT0014915		5:35363698–35363764 (+)	0.0 ± 0.09A	−0.219 ± 0.17AB	−0.674 ± 0.24B	Estrogen (down)
mmu-miR-30b-5p	MIMAT0000130	mir-30	15:68168977–68169072 (−)	0.0 ± 0.09A	−0.115 ± 0.07AB	−0.293 ± 0.09B	Estrogen (down)
mmu-mir-30c-1	MI0000547	mir-30	4:120442139–120442227 (−)	0.0 ± 0.08A	−0.192 ± 0.05AB	−0.262 ± 0.06B	Other (down)
mmu-miR-31-3p	MIMAT0004634	mir-31	4:88556461–88556566 (−)	0.0 ± 0.06A	−0.108 ± 0.11AB	−0.382 ± 0.15B	Estrogen (down)
mmu-miR-3102-5p	MIMAT0014933		7:108030820–108030923 (−)	0.0 ± 0.15A	−0.188 ± 0.19B	−0.493 ± 0.22B	Estrogen (down)
mmu-miR-3110-3p	MIMAT0014952		X:35563618–35563697 (+)	0.0 ± 0.1A	−0.180 ± 0.16AB	−0.558 ± 0.24B	Estrogen (down)
mmu-miR-32-3p	MIMAT0017050	mir-32	4:56908101–56908170 (−)	0.0 ± 0.16A	0.058 ± 0.12A	1.341 ± 0.63B	Estrogen (up)
mmu-miR-324-3p	MIMAT0000556	mir-324	11:69825545–69825633 (+)	0.0 ± 0.04A	−0.004 ± 0.07A	−0.300 ± 0.13B	Estrogen (down)
mmu-miR-324-5p	MIMAT0000555	mir-324	11:69825545–69825633 (+)	0.0 ± 0.05A	−0.140 ± 0.16AB	−0.480 ± 0.12B	Estrogen (down)
mmu-mir-325	MI0000597	mir-325	X:102574421–102574518 (−)	0.0 ± 0.03A	−0.280 ± 0.08B	−0.342 ± 0.07B	Other (down)
mmu-miR-325-5p	MIMAT0000558	mir-325	X:102574421–102574518 (−)	0.0 ± 0.14A	0.350 ± 0.1AB	0.606 ± 0.27B	Estrogen (up)
mmu-miR-330-3p	MIMAT0000569	mir-330	7:19766814–19766911 (+)	0.0 ± 0.07A	−0.159 ± 0.07AB	−0.271 ± 0.05B	Other (down)
mmu-miR-330-5p	MIMAT0004642	mir-330	7:19766814–19766911 (+)	0.0 ± 0.05A	−0.194 ± 0.16AB	−0.456 ± 0.13B	Estrogen (down)
mmu-miR-337-5p	MIMAT0004644	mir-337	12:110823999–110824095 (+)	0.0 ± 0.05A	−0.189 ± 0.12AB	−0.453 ± 0.11B	Estrogen (down)
mmu-miR-341-5p	MIMAT0017037	mir-341	12:110849710–110849805 (+)	0.0 ± 0.08A	−0.001 ± 0.07A	−0.370 ± 0.16B	Estrogen (down)
mmu-mir-343	MI0005494	mir-343	7:19971992–19972066 (+)	0.0 ± 0.08A	−0.143 ± 0.02AB	−0.306 ± 0.09B	Other (down)
mmu-mir-344-1	MI0000630	mir-344	7:69022656–69022750 (−)	0.0 ± 0.06A	−0.049 ± 0.07A	−0.310 ± 0.06B	Estrogen (down)
mmu-miR-344e-3p	MIMAT0014924	mir-344	7:68880423–68880488 (−)	0.0 ± 0.21A	−0.081 ± 0.11A	1.116 ± 0.68B	Estrogen (up)
mmu-mir-344f	MI0014098	mir-344	7:69191067–69191134 (−)	0.0 ± 0.08A	−0.166 ± 0.11A	−0.477 ± 0.08B	Estrogen (down)
mmu-miR-344f-5p	MIMAT0014931	mir-344	7:69191067–69191134 (−)	0.0 ± 0.11A	−0.252 ± 0.15A	−0.712 ± 0.13B	Estrogen (down)
mmu-miR-3470b	MIMAT0015641	mir-3470	16:44013965–44014090 (+)	0.0 ± 0.18A	0.427 ± 0.11B	0.410 ± 0.09B	Other (up)
mmu-miR-3473d	MIMAT0020632	mir-3473	8:113540350–113540430 (−)	0.0 ± 0.07A	−0.177 ± 0.09AB	−0.437 ± 0.16B	Estrogen (down)
mmu-miR-363-5p	MIMAT0017076	mir-363	X:50094870–50094944 (−)	0.0 ± 0.1A	−0.155 ± 0.09AB	−0.402 ± 0.07B	Estrogen (down)
mmu-mir-370	MI0001165	mir-370	12:110856468–110856546 (+)	0.0 ± 0.08A	−0.291 ± 0.11AB	−0.394 ± 0.12B	Estrogen (down)
mmu-miR-376c-3p	MIMAT0003183	mir-368	12:110960928–110961013 (+)	0.0 ± 0.05A	0.101 ± 0.09AB	0.280 ± 0.08B	Estrogen (up)
mmu-miR-378-3p	MIMAT0003151	mir-378	18:61557489–61557554 (−)	0.0 ± 0.1A	−0.550 ± 0.18B	−0.818 ± 0.27B	Other (down)
mmu-miR-378-5p	MIMAT0000742	mir-378	18:61557489–61557554 (−)	0.0 ± 0.11A	−0.246 ± 0.11AB	−0.343 ± 0.1B	Other (down)
mmu-mir-381	MI0000798	mir-154	12:110965032–110965106 (+)	0.0 ± 0.04A	−0.004 ± 0.07A	−0.307 ± 0.1B	Estrogen (down)
mmu-miR-383-3p	MIMAT0017082	mir-383	8:39315187–39315256 (−)	0.0 ± 0.08A	−0.201 ± 0.17AB	−0.499 ± 0.19B	Estrogen (down)
mmu-miR-383-5p	MIMAT0000748	mir-383	8:39315187–39315256 (−)	0.0 ± 0.07A	−0.370 ± 0.18AB	−0.706 ± 0.25B	Other (down)
mmu-miR-384-3p	MIMAT0001076	mir-384	X:102539621–102539708 (−)	0.0 ± 0.07A	0.162 ± 0.07AB	0.329 ± 0.09B	Estrogen (up)
mmu-mir-412	MI0001164	mir-412	12:110981499–110981578 (+)	0.0 ± 0.07A	−0.237 ± 0.09AB	−0.421 ± 0.07B	Other (down)
mmu-miR-412-5p	MIMAT0017173	mir-412	12:110981499–110981578 (+)	0.0 ± 0.08A	−0.353 ± 0.12B	−0.497 ± 0.08B	Other (down)
mmu-miR-421-5p	MIMAT0017273	mir-95	X:100768260–100768335 (−)	0.0 ± 0.02A	−0.310 ± 0.04B	−0.322 ± 0.09B	Other (down)
mmu-mir-431	MI0001524	mir-431	12:110828657–110828747 (+)	0.0 ± 0.04A	−0.187 ± 0.07AB	−0.312 ± 0.05B	Other (down)
mmu-mir-432	MI0012528	mir-432	12:110833166–110833240 (+)	0.0 ± 0.07A	−0.031 ± 0.05A	−0.410 ± 0.16B	Estrogen (down)
mmu-miR-432	MIMAT0012771	mir-432	12:110833166–110833240 (+)	0.0 ± 0.09A	−0.097 ± 0.13AB	−0.438 ± 0.18B	Estrogen (down)
mmu-mir-433	MI0001525	mir-433	12:110829925–110830048 (+)	0.0 ± 0.07A	−0.127 ± 0.05AB	−0.258 ± 0.05B	Other (down)
mmu-miR-452-5p	MIMAT0001637	mir-452	X:69507563–69507647 (−)	0.0 ± 0.09A	0.060 ± 0.09A	−0.316 ± 0.09B	Estrogen (down)
mmu-mir-465c-1	MI0005500	mir-465	X:64079130–64079210 (−)	0.0 ± 0.14A	0.500 ± 0.22AB	0.986 ± 0.39B	Estrogen (up)
mmu-mir-465c-2	MI0005501	mir-465	X:64085692–64085772 (−)	0.0 ± 0.11A	0.434 ± 0.2AB	1.022 ± 0.4B	Estrogen (up)
mmu-miR-466 h-5p	MIMAT0004884	mir-467	2:10436518–10436598 (+)	0.0 ± 0.19A	0.235 ± 0.09AB	0.451 ± 0.18B	Estrogen (up)
mmu-miR-466 l-5p	MIMAT0017322	mir-467	2:10437724–10437844 (+)	0.0 ± 0.06A	−0.250 ± 0.06AB	−0.314 ± 0.11B	Other (down)
mmu-mir-467a-9	MI0014074	mir-467	2:10420020–10420102 (+)	0.0 ± 0.03A	−0.383 ± 0.11B	−0.522 ± 0.16B	Other (down)
mmu-mir-467b	MI0004671	mir-467	2:10402875–10402947 (+)	0.0 ± 0.07A	−0.342 ± 0.14AB	−0.459 ± 0.15B	Other (down)
mmu-mir-467c	MI0005512	mir-467	2:10395558–10395654 (+)	0.0 ± 0.14A	−0.289 ± 0.06AB	−0.358 ± 0.11B	Other (down)
mmu-miR-468-3p	MIMAT0002109		6:81846593–81846670 (−)	0.0 ± 0.08A	−0.157 ± 0.09AB	−0.548 ± 0.27B	Estrogen (down)
mmu-mir-490	MI0005002	mir-490	6:36371742–36371825 (+)	0.0 ± 0.09A	−0.332 ± 0.07B	−0.402 ± 0.09B	Other (down)
mmu-miR-490-5p	MIMAT0017261	mir-490	6:36371742–36371825 (+)	0.0 ± 0.1A	−0.244 ± 0.13AB	−0.414 ± 0.12B	Other (down)
mmu-miR-497-5p	MIMAT0003453	mir-497	11:70048219–70048302 (+)	0.0 ± 0.14A	0.346 ± 0.14AB	0.414 ± 0.11B	Other (up)
mmu-mir-500	MI0004702	mir-500	X:6814809–6814900 (−)	0.0 ± 0.06A	−0.031 ± 0.1A	−0.369 ± 0.17B	Estrogen (down)
mmu-miR-504-3p	MIMAT0017277	mir-504	X:56350835–56350913 (−)	0.0 ± 0.05A	−0.370 ± 0.16AB	−0.493 ± 0.21B	Other (down)
mmu-miR-504-5p	MIMAT0004889	mir-504	X:56350835–56350913 (−)	0.0 ± 0.15A	0.126 ± 0.05A	0.421 ± 0.1B	Estrogen (up)
mmu-mir-5098	MI0018006	mir-1954	5:77701782–77701863 (+)	0.0 ± 0.17A	0.208 ± 0.09AB	0.488 ± 0.1B	Estrogen (up)
mmu-mir-5100	MI0018008		11:60542165–60542228 (+)	0.0 ± 0.07A	0.323 ± 0.04B	0.254 ± 0.07B	Other (up)
mmu-miR-5109	MIMAT0020617		5:17282567–17282653 (−)	0.0 ± 0.05A	0.381 ± 0.09B	0.298 ± 0.09B	Other (up)
mmu-miR-5114	MIMAT0020622		19:44377661–44377721 (+)	0.0 ± 0.1A	−0.183 ± 0.1AB	−0.476 ± 0.12B	Estrogen (down)
mmu-miR-5115	MIMAT0020623		2:72850911–72850984 (−)	0.0 ± 0.15A	0.297 ± 0.1AB	0.580 ± 0.2B	Estrogen (up)
mmu-miR-5124	MIMAT0020634		13:40961160–40961231 (+)	0.0 ± 0.07A	−0.249 ± 0.08AB	−0.277 ± 0.06B	Other (down)
mmu-miR-5131	MIMAT0020642		14:46277636–46277728 (−)	0.0 ± 0.04A	−0.067 ± 0.07A	−0.353 ± 0.15B	Other (down)
mmu-miR-540-3p	MIMAT0003167	mir-540	12:110824290–110824356 (+)	0.0 ± 0.03A	−0.162 ± 0.08AB	−0.415 ± 0.11B	Estrogen (down)
mmu-mir-543	MI0003519	mir-329	12:110955468–110955543 (+)	0.0 ± 0.09A	−0.189 ± 0.06AB	−0.329 ± 0.09B	Other (down)
mmu-miR-592-5p	MIMAT0003730	mir-592	6:27886655–27886750 (−)	0.0 ± 0.08A	−0.247 ± 0.11AB	−0.496 ± 0.11B	Other (down)
mmu-mir-615	MI0005004	mir-615	15:102845341–102845432 (+)	0.0 ± 0.15A	−0.315 ± 0.09AB	−0.542 ± 0.11B	Other (down)
mmu-miR-652-3p	MIMAT0003711	mir-652	X:139173543–139173640 (+)	0.0 ± 0.07A	−0.394 ± 0.24AB	−0.652 ± 0.18B	Other (down)
mmu-miR-652-5p	MIMAT0017260	mir-652	X:139173543–139173640 (+)	0.0 ± 0.05A	−0.025 ± 0.08A	−0.371 ± 0.15B	Estrogen (down)
mmu-miR-665-5p	MIMAT0017238	mir-665	12:110824524–110824617 (+)	0.0 ± 0.12A	−0.205 ± 0.19AB	−0.531 ± 0.15B	Estrogen (down)
mmu-miR-666-3p	MIMAT0004823	mir-666	12:110955295–110955393 (+)	0.0 ± 0.11A	0.040 ± 0.11A	−0.401 ± 0.17B	Estrogen (down)
mmu-miR-666-5p	MIMAT0003737	mir-666	12:110955295–110955393 (+)	0.0 ± 0.05A	−0.097 ± 0.12AB	−0.351 ± 0.13B	Estrogen (down)
mmu-mir-668	MI0004134	mir-668	12:110972942–110973007 (+)	0.0 ± 0.06A	−0.208 ± 0.1AB	−0.369 ± 0.1B	Other (down)
mmu-miR-668-5p	MIMAT0017237	mir-668	12:110972942–110973007 (+)	0.0 ± 0.07A	−0.235 ± 0.14AB	−0.502 ± 0.11B	Estrogen (down)
mmu-mir-669a-4	MI0014054	mir-467	2:10400942–10401028 (+)	0.0 ± 0.09A	−0.160 ± 0.08AB	−0.325 ± 0.06B	Other (down)
mmu-miR-669b-5p	MIMAT0003476	mir-467	2:10389417–10389513 (+)	0.0 ± 0.09A	−0.334 ± 0.06A	0.503 ± 0.18B	Estrogen (up)
mmu-miR-669 h-3p	MIMAT0005842	mir-467	2:10439782–10439906 (+)	0.0 ± 0.21A	−0.233 ± 0.17AB	−0.655 ± 0.26B	Estrogen (down)
mmu-miR-669 l-3p	MIMAT0017345	mir-467	2:10390598–10390695 (+)	0.0 ± 0.09A	0.203 ± 0.23AB	0.639 ± 0.22B	Estrogen (up)
mmu-miR-670-3p	MIMAT0017242	mir-670	2:94101457–94101556 (−)	0.0 ± 0.03A	−0.336 ± 0.11B	−0.333 ± 0.06B	Other (down)
mmu-miR-671-3p	MIMAT0004821	mir-671	5:24097932–24098029 (+)	0.0 ± 0.1A	−0.241 ± 0.15A	−0.779 ± 0.25B	Estrogen (down)
mmu-mir-673	MI0004601	mir-673	12:110810200–110810290 (+)	0.0 ± 0.07A	−0.220 ± 0.07AB	−0.347 ± 0.13B	Other (down)
mmu-miR-673-3p	MIMAT0004824	mir-673	12:110810200–110810290 (+)	0.0 ± 0.07A	−0.394 ± 0.14AB	−0.500 ± 0.24B	Other (down)
mmu-miR-679-3p	MIMAT0017248		12:110953787–110953860 (+)	0.0 ± 0.09A	−0.429 ± 0.08B	−0.434 ± 0.18B	Other (down)
mmu-miR-679-5p	MIMAT0003455		12:110953787–110953860 (+)	0.0 ± 0.07A	−0.239 ± 0.13AB	−0.367 ± 0.11B	Other (down)
mmu-mir-683-2	MI0010690	mir-683	13:50696341–50696449 (−)	0.0 ± 0.06A	−0.236 ± 0.1AB	−0.444 ± 0.12B	Other (down)
mmu-miR-691	MIMAT0003470		16:74342235–74342312 (−)	0.0 ± 0.17A	0.063 ± 0.14A	0.731 ± 0.18B	Estrogen (up)
mmu-miR-700-5p	MIMAT0017256		4:134972470–134972548 (−)	0.0 ± 0.07A	−0.252 ± 0.09AB	−0.435 ± 0.13B	Other (down)
mmu-mir-702	MI0004686	mir-702	5:137467303–137467411 (+)	0.0 ± 0.09A	−0.414 ± 0.12B	−0.359 ± 0.1B	Estrogen (down)
mmu-mir-707	MI0004691		7:52105069–52105141 (+)	0.0 ± 0.06A	−0.337 ± 0.05B	−0.362 ± 0.07B	Other (down)
mmu-mir-758	MI0004129	mir-379	12:110951020–110951100 (+)	0.0 ± 0.04A	−0.251 ± 0.07AB	−0.353 ± 0.13B	Estrogen (down)
mmu-miR-762	MIMAT0003892	mir-762	4:108690260–108690335 (+)	0.0 ± 0.23A	0.089 ± 0.12AB	0.485 ± 0.17B	Estrogen (up)
mmu-miR-873-5p	MIMAT0004936	mir-873	4:36615543–36615619 (−)	0.0 ± 0.12A	−0.367 ± 0.07B	−0.448 ± 0.11B	Other (down)
mmu-mir-874	MI0005479	mir-874	13:58124486–58124561 (−)	0.0 ± 0.1A	−0.034 ± 0.07A	−0.300 ± 0.09B	Estrogen (down)
mmu-miR-874-3p	MIMAT0004853	mir-874	13:58124486–58124561 (−)	0.0 ± 0.08A	−0.247 ± 0.11A	−0.613 ± 0.17B	Estrogen (down)
mmu-miR-874-5p	MIMAT0017268	mir-874	13:58124486–58124561 (−)	0.0 ± 0.11A	−0.104 ± 0.09A	−0.515 ± 0.15B	Estrogen (down)
mmu-miR-877-5p	MIMAT0004861	mir-877	17:36097675–36097759 (−)	0.0 ± 0.07A	0.129 ± 0.13A	−0.360 ± 0.09B	Estrogen (down)
mmu-mir-92a-1	MI0000719	mir-25	14:115443649–115443728 (+)	0.0 ± 0.08A	−0.063 ± 0.07AB	−0.283 ± 0.08B	Estrogen (down)
mmu-miR-93-5p	MIMAT0000540	mir-17	5:138606751–138606838 (−)	0.0 ± 0.03A	−0.101 ± 0.09AB	−0.311 ± 0.09B	Estrogen (down)
mmu-mir-96	MI0000583	mir-96	6:30119446–30119551 (−)	0.0 ± 0.05A	0.116 ± 0.08A	−0.282 ± 0.1B	Estrogen (down)
mmu-miR-98-3p	MIMAT0017023	let-7	X:148347757–148347864 (+)	0.0 ± 0.19A	0.290 ± 0.13AB	0.511 ± 0.18B	Estrogen (up)

Different levels of superscript letter indicates statistically significant effect (false discovery rate ≤ 0.05)