Table 2.
Change in percentage of iv antibiotic prescriptions >72 h and median antibiotic duration (days) during the pre-intervention and post-intervention period and comparison between the intervention and control group using interrupted time series analysis
| Slope during the pre-intervention period (SE) | P | Change in level after interventiona (SE) | P | Slope during the post-intervention periodb (SE) | P | |
|---|---|---|---|---|---|---|
| Percentage of iv antibiotic prescriptions >72 h (%) | ||||||
| Intervention group | −0.03 (0.42) | 0.94 | −19.30 (4.41) | <0.01 | 0.48 (0.59) | 0.43 |
| Control group | −0.36 (0.25) | 0.16 | −6.12 (2.61) | <0.05 | −0.26 (0.35) | 0.46 |
| Difference between intervention and control group | 0.33 (0.48) | 0.50 | −13.17 (5.13) | <0.05 | 0.74 (0.68) | 0.29 |
| Median duration of iv antibiotics (days) | ||||||
| Intervention group | −0.02 (0.03) | 0.49 | −0.77 (0.29) | 0.015 | 0.02 (0.04) | 0.63 |
| Control group | −0.38 (0.03) | 0.16 | −0.15 (0.28) | 0.59 | 0.04 (0.04) | 0.32 |
| Difference between intervention and control group | 0.02 (0.04) | 0.62 | 0.62 (0.41) | 0.14 | −0.02 (0.05) | 0.72 |
aMeasures the immediate impact of the intervention
bMeasures the long-term impact over time of the intervention