Fig. 1.

Seizures in LGI1-antibody encephalitis. A. EEG showing multifocal epileptiform discharges independently over the left mid to posterior temporal (*), left frontotemporal (**), left centroparietal (π) and right hemispheric (ππ) electrodes, on the background of excess of slow wave activity (sensitivity 7microV/mm, time base 30 mm/s). B. Relationship between 24-month fall in modified Rankin Score and observed seizure frequency (Spearman’s correlation r = −0.76, p = 0.001). C. Seizure frequency over one per hour associates with a more limited reduction in modified Rankin Score (mRS) at two-year follow-up (Mann Whitney U test p = 0.0025).