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. Author manuscript; available in PMC: 2018 May 8.
Published in final edited form as: Angew Chem Int Ed Engl. 2017 Apr 11;56(20):5603–5606. doi: 10.1002/anie.201702274

Figure 3.

Figure 3

Figure 3

Left panel. Correlation between relaxivity and molecular weight for the Gd complexes discussed here. Open circles: Complexes reported in reference 4. The solid line represents a linear regression (r2 = 0.99) . Solid triangles: 4d, 4e (pH 6) . Open triangles: 4a, 4b, 4c, 4e (pH 9) . Right panel. pH – relaxivity titration of 4e between pH 4.8 and pH 9.4. Filled circles represent measured data points, the solid red line represents a fit by the Henderson-Hasselbach equation, with a calculated pKa of 7.98 ± 0.07.