Table 1.
Baseline characteristics of patients in the cohort compared to the SAMMPRIS cohort
| Variable | Cohort (n=99) | SAMMPRIS (n=227) |
P- value |
|---|---|---|---|
| Mean age (SD) in years | 68.2 (11.2) | 59.5 (11.8) | <0.001 |
| Male, n (%) | 51 (51.5) | 82 (36.1) | 0.013 |
| Race, n (%) | <0.001 | ||
| White | 38 (38.4) | 161 (70.9) | |
| African-American | 53 (53.5) | 50 (22.0) | |
| Other | 8 (8.1) | 16 (7.0) | |
| Hypertension, n (%) | 81 (81.8) | 203 (89.4) | 0.088 |
| Diabetes mellitus, n (%) | 56 (56.6) | 103 (45.4) | 0.082 |
| Hemoglobin A1c, n (%) | |||
| <5.7%, n (%) | 28 (28.3) | - | |
| 5.8 – 7.9%, n (%) | 42 (42.4) | - | |
| >7.9%, n (%) | 29 (29.3) | - | |
| Dyslipidemia, n (%) | 79 (79.8) | 203 (89.4) | 0.031 |
| LDL level, n (%) | |||
| <70 mg/dL, n (%) | 20 (20.2) | - | |
| 70–100 mg/dL, n (%) | 33 (33.3) | - | |
| >100 mg/dL, n (%) | 46 (46.5) | - | |
| Coronary artery disease, n (%) | 22 (22.2) | 59 (26.0) | 0.559 |
| Prior history of ischemic stroke or TIA, n (%) | 45 (45.5) | 58 (25.6) | <0.001 |
| Current smoking, n (%) | 23 (23.2) | 69 (30.4) | 0.235 |
| Statin therapy, n (%) | 53 (53.5) | 196 (86.3) | |
| NIHSS score >1, n (%) | 62 (62.6) | 88 (38.8) | <0.001 |
| Location of ICAD, n (%) | 0.002 | ||
| Middle cerebral artery | 30 (30.3) | 105 (46.3) | |
| Intracranial vertebral artery | 16 (16.2) | 22 (9.7) | |
| Intracranial internal carotid artery | 37 (37.4) | 49 (21.6) | |
| Basilar artery | 16 (16.2) | 51 (22.5) | |
| Degree of stenosis of ICAD, n (%) | <0.001 | ||
| Moderate | 30 (30.3) | N/A | |
| Severe | 69 (69.7) | 227 (100) | |
| Prior infarcts in the territory, n (%) | 30 (40.8) | 75 (33.0) | 0.700 |
| Discharge Medications | <0.001 | ||
| DAPT | 67 (67.5) | 227 (100) | |
| HDS | 65 (65.4) | 227 (100) | |
| DAPT plus HDS therapy | 48 (48.4) | 227 (100) |