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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Aquat Toxicol. 2017 Jun 21;190:1–10. doi: 10.1016/j.aquatox.2017.06.019

Figure 5.

Figure 5

BDE-47 functions as a false positive for TH signaling. A–C. Morphological endpoints, presented as a ratio of effects of BDE-47 vs. vehicle control. Boxes represent the 25th–75th percentile values, and the line is at the median; whiskers show maximum and minimum values (n = 15). D. Effect of BDE-47 on cellular proliferation in the RHR. E. Effect of BDE-47 on TRE-luc activation in tadpole heads in both agonist and antagonist modes. Bars represent the mean with standard error (n = 15). Significantly different from vehicle control at *, p < 0.05; ***, p<0.001; ****, p<0.0001 as determined by 1-way ANOVA with Sidak’s multiple comparison test (MCT).