Table 1. The main characteristics of the study groups.
Community-acquired pneumonia | Severe acute symptoms | Patients with underlying conditions for severe influenza | P | ||||
---|---|---|---|---|---|---|---|
n = 240 | n = 647 | n = 352 | |||||
moy±DS | moy±DS | moy±DS | |||||
n | % | n | % | n | % | ||
Risk factors for severe influenza infection | |||||||
Age | 68.5±18.7 | 70.6±18.5 | 55±21.1 | 0.002 | |||
Age ≥65 years | 153 | 63.8 | 444 | 68.6 | 127 | 36.1 | 0.00001 |
Asthma | 44 | 18.7 | 259 | 40.6 | 38 | 11.2 | 0.00001 |
Bronchopulmonary dysplasia | 5 | 2.1 | 20 | 3.1 | 1 | 0.3 | 0.01 |
Cystic fibrosis | 23 | 9.8 | 34 | 5.3 | 13 | 3.9 | 0.009 |
Chronic respiratory failure | 19 | 8.1 | 94 | 14.8 | 10 | 3 | 0.000001 |
Cardiac failure | 27 | 11.5 | 126 | 19.8 | 20 | 5.9 | 0.000001 |
Cardiac valvulopathy | 9 | 3.8 | 31 | 4.9 | 4 | 1.2 | 0.01 |
Congenital heart disease | 3 | 1.3 | 14 | 2.2 | 4 | 1.2 | 0.4 |
Cardiovascular disease | 14 | 6 | 57 | 9 | 10 | 3 | 0.002 |
Renal failure | 21 | 8.9 | 68 | 10.7 | 19 | 5.6 | 0.03 |
Nephrotic syndrome | 1 | 0.4 | 1 | 0.2 | 4 | 1.2 | 0.09% |
Sickle-cell anemia | 0 | 0 | 1 | 0.2 | 3 | 0,9 | 0.1 |
Hepatic failure | 1 | 0.4 | 3 | 0.5 | 0 | 0 | 0.5 |
Diabetes | 37 | 15.7 | 123 | 19.3 | 43 | 12.7 | 0.03 |
Systemic corticosteroid therapy | 14 | 6 | 43 | 6.8 | 18 | 5.3 | 0.7 |
Leukemia or Lymphoma | 6 | 2.6 | 5 | 0.8 | 2 | 0.6 | 0.05 |
Immunosuppression | 14 | 6 | 24 | 3.8 | 18 | 5.3 | 0.3 |
Cancer | 11 | 4.7 | 31 | 4.9 | 11 | 3.3 | 0.5 |
HIV infection | 10 | 4.3 | 14 | 2.2 | 11 | 3.3 | 0.2 |
CD4 count | 196±347 | 145±174 | 15–19 | 0.4 | |||
Obesity | 11 | 4.70% | 44 | 6.9 | 9 | 2.7 | 0.02 |
Pregnancy | 1 | 0.4 | 6 | 0,9 | 4 | 1.2 | 0.6 |
At least one of the above | 177 | 75.3 | 640 | 52.7 | 339 | 27.9 | 0.00001 |
Signs of severity | |||||||
Polypnea | 34 | 14.17% | 124 | 12.41% | 0 | 0 | 0.5 |
Cyanosis | 5 | 2.08% | 28 | 2.80% | 0 | 0 | 0.0002 |
Oxygen saturation Spa02 < 95% | 108 | 45.00% | 416 | 41.64% | 0 | 0 | 0.00001 |
Pneumonia | 118 | 49.2 | 167 | 25.8 | 0 | 0 | 0.00001 |
Wheeze | 52 | 21.67% | 259 | 25,93% | 0 | 0 | 0.0001 |
Tachycardia | 35 | 14.58% | 120 | 12.01% | 0 | 0 | 0.000001 |
Hypotension | 17 | 7.08% | 45 | 4.50% | 0 | 0 | 0.000001 |
Areas of mottled skin | 9 | 3.75% | 42 | 4.20% | 0 | 0 | 0.000001 |
Discomfort | 10 | 4.17% | 39 | 3.90% | 0 | 0 | 0.00002 |
Changes in mental status | 12 | 5% | 37 | 3.70% | 0 | 0 | 0.00004 |
Oliguria | 2 | 0.83% | 5 | 0.50% | 0 | 0 | 0.2 |
At least one of the above | 177 | 73.8% | 591 | 59.2% | 0 | 0 | 0.00001 |