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. 2017 Aug 16;12(8):e0183021. doi: 10.1371/journal.pone.0183021

Table 1. Genotypes for top GWAS SNP and LINE-1 insertion in Swedish Vallhunds from the UK and Finland.

Table 1a UK dogs (24 cases and 97 controls)
Retinopathy status
SNP_BICF2G630207991 genotypea Case n (freq.) Control n (freq.) Total
T/T 3 (0.13) 25 (0.26) 28
T/C 6 (0.25) 67 (0.69) 73
C/C 15 (0.63) 5 (0.05) 20 P-value: 4.7 x 10−9
LINE-1 insertion genotype
Wildtype 3 (0.13) 28 (0.29) 31
Heterozygote 6 (0.25) 67 (0.69) 73
LINE-1 ins 15 (0.63) 2 (0.02) 17 P-value 6.0 x 10−11
Table 1b Finnish dogs (49 cases and 89 controls)
Retinopathy status
SNP_BICF2G630207991 genotypea Case n (freq.) Control n (freq.) Total
T/T 0 (0.00) 26 (0.29) 26
T/C 7 (0.14) 51 (0.57) 58
C/C 42 (0.86) 12 (0.13) 54 P-value 1.3 x 10−17
LINE-1 insertion genotype
Wildtype 0 (0.00) 28 (0.31) 28
Heterozygote 7 (0.14) 51 (0.57) 58
LINE-1 ins 42 (0.86) 10 (0.11) 52 P-value 4.3 x 10−19

a For SNP_BICF2G630207991 the risk allele is C