Fig. S1.

Bias of the ROH-based inbreeding measures ($F_{\mathrm{ROH}}$) expressed as the linear regression of the inbreeding coefficient at causal variants ($F_{QTL}$) over $F_{\mathrm{ROH}}$. Unbiasedness is equivalent to a regression coefficient of 1 (red horizontal line). All 3,857,369 SNPs were considered as causal variants. Assumption A: The expectations of dominance effects are equal for all SNPs. Assumption B: The expectation of the dominance effect of each SNP is inversely proportional to the variance of the minor allele count for that SNP.