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. 2017 Jul 26;114(32):8602–8607. doi: 10.1073/pnas.1621096114

Fig. S2.

Fig. S2.

Averaged SEs of ID estimates from 1,000 simulated datasets. Datasets were simulated assuming a true ID parameter b=3 (horizontal gray line) phenotypic SD for complete inbreeding. In scenario 1 the m = 1,000 causal variants were randomly sampled from all observed SNPs, whereas in scenarios 2 and 3 they were respectively sampled from low- and high-LD regions of the genome. In A the expectation of the dominance effects (δj for the jth causal variant) is constant (neutral model) whereas in B δj is inversely proportional to the variance of the minor allele count at each causal variant. FHOM, excess homozygosity inbreeding measure; FROH(1) and FROH(2), runs of homozygosity-based inbreeding measures; FUNI, measure of inbreeding based on correlation between uniting gametes; LDMS, LD and MAF stratified inference.