Averaged SEs of ID estimates from 1,000 simulated datasets. Datasets were simulated assuming a true ID parameter (horizontal gray line) phenotypic SD for complete inbreeding. In scenario 1 the = 1,000 causal variants were randomly sampled from all observed SNPs, whereas in scenarios 2 and 3 they were respectively sampled from low- and high-LD regions of the genome. In A the expectation of the dominance effects ( for the th causal variant) is constant (neutral model) whereas in B
is inversely proportional to the variance of the minor allele count at each causal variant. , excess homozygosity inbreeding measure; and , runs of homozygosity-based inbreeding measures; , measure of inbreeding based on correlation between uniting gametes; LDMS, LD and MAF stratified inference.