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Gene expression changes observed upon Hdac3 loss associated with failed pre–B-cell differentiation. (A) Heatmap depicting significant gene expression changes between Hdac3+/+ and Hdac3Δ/− pro-B cells as determined by RNA-seq analysis. (B) Fragments per kilobase of transcript per million mapped reads (FPKM) values of significantly changed genes that contribute to VDJ recombination. (C) FPKM values of Igll1, Vpreb1, c-Kit, and p21.
