Fig. 3.

The 15.2-Å cryo-EM CtUGGT reconstruction confirms mobility of TRXL2. (A–C) Three orthogonal views of the overlay of three crystallographically independent molecules of WT CtUGGT across three crystal forms. Helices are represented by cylinders. Yellow: P6₁22 form, open conformation; green: P6₁ form, intermediate conformation; and blue: P4₃ form, closed conformation (molecule A). The models have been superimposed with the main class of the 15.2-Å cryo-EM reconstruction. The cryo-EM reconstruction contour level encloses a volume corresponding to the protein mass.