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. 2017 Jul 24;114(32):E6556–E6565. doi: 10.1073/pnas.1703791114

Fig. 1.

Fig. 1.

CDCP1 lowers intracellular LD abundance of breast cancer cells. (A) CDCP1 knockdown increases LD abundance in three TNBC cell lines: (i) representative 40× CARS images; (ii) quantitation of CARS; (iii) Western blot confirming CDCP1 knockdown. (B) CDCP1 overexpression decreases LD abundance in three TNBC cell lines and ER+ MCF7 breast cancer cell line not expressing endogenous CDCP1: (i) representative 40× CARS images; (ii) quantitation of CARS; (iii) Western blot confirming CDCP1 overexpression. n = 3 for A and B. P values analyzed by one-way ANOVA with multiple comparison post hoc t test and error bars represent SEMs; *P < 0.05, **P < 0.01. shScr, shScramble; shC1 & 2, shCDCP1-1 and 2.