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. 2017 Jul 24;114(32):8631–8636. doi: 10.1073/pnas.1708106114

Fig. S2.

Fig. S2.

Fractions of hyperactive neurons after short-term treatment with BACE inhibitor. Fractions of hyperactive neurons relative to all imaged neurons in WT mice (blue bar; n = 5), untreated APP23xPS45 mice (red bar; n = 8), and APP23xPS45 mice after short-term (yellow bar; n = 5) and long-term (green bar; n = 10) NB-360 treatment (2.48 ± 1.20% for WT vs. 50.60 ± 9.53% for control vs. 29.22 ± 9.69% for short-term treatment vs. 11.15 ± 4.62% for long-term treatment; P > 0.05, control vs. short-term treatment). Gray circles represent individual animals. ns, not significant. Error bars represent mean ± SEM.