TABLE 1.

Blood chemistry parameters at baseline (n = 82) and after 16 weeks on amino acid-based formula (n = 66)

		Baseline		After 16 weeks on AAF
Parameter	Reference value	Mean (SD)	n (%)	Mean (SD)	n (%)
Ca, mmol/L	2.25–2.74	2.67 (0.14)	1 (1%)	2.62 (0.11)	0
P, mmol/L	1.36–2.62 (<1 y)	2.05 (0.25)	1 (1%)	1.97 (0.20)	0
	1.03–1.97 (≥1 y)	—		1.86 (0.24)	0
Cl, mmol/L	94–112	104 (3.2)	1 (1%)	104 (2.3)	0
Na, mmol/L	132–147	140 (3.3)	1 (1%)	140 (2.3)	0
K, mmol/L	3.7–5.6 (<1 y)	5.0 (0.52)	0	4.6 (0.29)	0
	3.4–5.4 (≥1 y)	—		4.6 (0.48)	0
Mg, mmol/L	0.70–0.98 (<30 day)	0.89 (0.05)	0	0.92 (0.05)	0
	0.66–1.03 (M; ≥30 day)	0.95 (0.06)	0	0.95 (0.07)	0
	0.78–0.98 (F; ≥30 day)	0.95 (0.05)	0	0.96 (0.07)	0
Ferritin, μg/L	≥12	61 (55)	6 (7%)	24 (18)	15 (22%)
Hemoglobin, g/L	100–200 (<30 day)	168 (4.6)	0	—	—
	100–140 (<5 mo)	115 (11)	4 (7%)	122 (8.5)	0
	105–135 (≥5 mo)	119 (9.4)	2 (8%)	121 (9.0)	2 (4%)
Albumin, g/L	24–48 (<30 day)	38 (2.3)	0	—
	28–48 (≥30 day)	39 (5.2)	3 (4%)	41 (3.7)	0
Total protein, g/L	54–74 (<3 mo)	58 (3.4)	1 (4%)
	55–71 (≥3 mo)	61 (6.5)	5 (9%)	64 (4.3)	0

Mean (SD) and number (%) of infants having a mineral status below the lowest range of the reference value.

AAF = amino acid-based formula; Ca = calcium; Cl = chloride; K = potassium; Mg = magnesium; Na = sodium; P = phosphorus; y = years.