. Author manuscript; available in PMC: 2017 Aug 16.

Published in final edited form as: J Am Chem Soc. 2015 Jun 19;137(25):8294–8307. doi: 10.1021/jacs.5b04843

Table 1.

Isotopic labeling patterns of peptide samples for ssNMR measurements. All Aβ40 samples were also perdeuterated at V12, V18, V24, V36, and V39.

peptide sample	labeling of component A	labeling of component B	A:B ratio
Aβ40 I	U-¹⁵N,¹³C at F19, L34, G38; ¹³CO at A30	U-¹⁵N,¹³C at F19, L34, G38; ¹³C_βat A30	50:50
Aβ40 II	¹³CO at A21	¹³C_βat A21	28:72
Aβ40 III	¹³CO at A30	¹³C_βat A30	56:44
Aβ40 IV	¹³CO at G33	¹³C_αat G33	40:60
Aβ_11-25	¹³CO at F20; ¹³C_β at A21; ¹⁵N at L17	--	--