Table 1. Incidence and frequency of tumorigenesis.
Adult mouse + treatment | # of animals | Incidence of epidermal hyperplasia (%) | Incidence of Sebaceous hyperplasia (%) | Incidence of Sebaceous carcinoma (%) | # Sebaceous carcinoma per mouse | Incidence of lymph node metastasis (%) |
---|---|---|---|---|---|---|
Snail Tg | 10 | 0 | 100 | 0 | 0 | 0 |
WT + DMBA/TPA | 10 | 30 | 0 | 0 | 0 | 0 |
Snail Tg + DMBA/TPA | 16 | 100 | 100 | 100 | 20.56±10.3 | 93.8 |