Figure 4.
A, (left) Average tumor sizes in animals treated with XL147, R788, or both (N = 7). Values are shown as mean +/− S.E.M. ranges. (right) CBRC013 PDX tumor sizes after three weeks of treatment. B, (left) Average CBRC029 tumor sizes in animals treated with perifosine, R788, or both (N = 7–8). Values are shown as mean +/− S.E.M. ranges. (right) CBRC029 PDX tumor sizes after three weeks of treatment. C, (left) Average CBRC029 tumor sizes in animals treated with perifosine, fingolimod, or both (N = 8). Values are shown as mean +/− S.E.M. ranges. (right) CBRC029 PDX tumor sizes after three weeks of treatment. D, (left) Average CBRC029 tumor sizes in animals treated with dasatinib, tozasertib, or both (N = 3–7). Values are shown as mean +/− S.E.M. ranges. (right) CBRC029 PDX tumor sizes after three weeks of treatment.