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. 2017 Aug 16;7:64. doi: 10.1186/s13550-017-0316-x

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 3 — ROI definition in a patient with a glioblastoma in the right temporal lobe. a The tumour volume as delineated by TBR > 1.8 based on data reconstruction of centre A. b The 90% isocontour of the 10–30-min image for TAC generation in centre A and c the tumour volume as delineated by a TBR > 1.6 in centre B which is also used TAC generation