Figure 6.
Effects of GFAP-modulating agents on astrocytic uptake of Bauer peptide. (A) Exemplary fluorescence images showing temporal changes of fluorescence intensity of astrocytes that were preloaded with Bauer peptide (20 μM, 2–4 h at 35°C) in the SON. From left to the right the columns were control, OT (1 nM), OTRA (1 μM, from 5 min before OT) plus OT, PD98059 (20 μM) and IPT (10 μM), respectively. (B) Summary graphs. Note that, *P < 0.05, **P < 0.01 compared to the controls; †P < 0.05 and ††P < 0.01 compared with those at 5 min. Other annotations refer to Figures 1, 4.